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Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Yang Z, Johnson BA, Meliopoulos VA, Ju X, Zhang P, Hughes MP, Wu J, Koreski KP, Clary JE, Chang TC, Wu G, Hixon J, Duffner J, Wong K, Lemieux R, Lokugamage KG, Alvarado RE, Crocquet-Valdes PA, Walker DH, Plante KS, Plante JA, Weaver SC, Kim HJ, Meyers R, Schultz-Cherry S, Ding Q, Menachery VD, Taylor JP. Yang Z, et al. Cell Rep. 2024 Mar 26;43(3):113965. doi: 10.1016/j.celrep.2024.113965. Epub 2024 Mar 15. Cell Rep. 2024. PMID: 38492217 Free PMC article.
Spike mutation D614G alters SARS-CoV-2 fitness.
Plante JA, Liu Y, Liu J, Xia H, Johnson BA, Lokugamage KG, Zhang X, Muruato AE, Zou J, Fontes-Garfias CR, Mirchandani D, Scharton D, Bilello JP, Ku Z, An Z, Kalveram B, Freiberg AN, Menachery VD, Xie X, Plante KS, Weaver SC, Shi PY. Plante JA, et al. Nature. 2021 Apr;592(7852):116-121. doi: 10.1038/s41586-020-2895-3. Epub 2020 Oct 26. Nature. 2021. PMID: 33106671 Free PMC article.
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Johnson BA, Zhou Y, Lokugamage KG, Vu MN, Bopp N, Crocquet-Valdes PA, Kalveram B, Schindewolf C, Liu Y, Scharton D, Plante JA, Xie X, Aguilar P, Weaver SC, Shi PY, Walker DH, Routh AL, Plante KS, Menachery VD. Johnson BA, et al. PLoS Pathog. 2022 Jun 21;18(6):e1010627. doi: 10.1371/journal.ppat.1010627. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35728038 Free PMC article.
Catch Me if You Can: Superspreading of COVID-19.
Lakdawala SS, Menachery VD. Lakdawala SS, et al. Trends Microbiol. 2021 Oct;29(10):919-929. doi: 10.1016/j.tim.2021.05.002. Epub 2021 May 11. Trends Microbiol. 2021. PMID: 34059436 Free PMC article. Review.
Engineering SARS-CoV-2 using a reverse genetic system.
Xie X, Lokugamage KG, Zhang X, Vu MN, Muruato AE, Menachery VD, Shi PY. Xie X, et al. Nat Protoc. 2021 Mar;16(3):1761-1784. doi: 10.1038/s41596-021-00491-8. Epub 2021 Jan 29. Nat Protoc. 2021. PMID: 33514944 Free PMC article. Review.
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions.
Garvanska DH, Alvarado RE, Mundt FO, Lindqvist R, Duel JK, Coscia F, Nilsson E, Lokugamage K, Johnson BA, Plante JA, Morris DR, Vu MN, Estes LK, McLeland AM, Walker J, Crocquet-Valdes PA, Mendez BL, Plante KS, Walker DH, Weisser MB, Överby AK, Mann M, Menachery VD, Nilsson J. Garvanska DH, et al. EMBO Rep. 2024 Feb;25(2):902-926. doi: 10.1038/s44319-023-00043-z. Epub 2024 Jan 2. EMBO Rep. 2024. PMID: 38177924 Free PMC article.
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Johnson BA, Xie X, Bailey AL, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Winkler ES, Swetnam D, Plante JA, Aguilar P, Plante KS, Popov V, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Diamond MS, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4. Epub 2021 Jan 25. Nature. 2021. PMID: 33494095 Free PMC article.
SARS-CoV-2 hijacks fragile X mental retardation proteins for efficient infection.
Garvanska DH, Alvarado RE, Mundt FO, Nilsson E, Duel JK, Coscia F, Lindqvist R, Lokugamage K, Johnson BA, Plante JA, Morris DR, Vu MN, Estes LK, McLeland AM, Walker J, Crocquet-Valdes PA, Mendez BL, Plante KS, Walker DH, Weisser MB, Overby AK, Mann M, Menachery VD, Nilsson J. Garvanska DH, et al. bioRxiv [Preprint]. 2023 Sep 1:2023.09.01.555899. doi: 10.1101/2023.09.01.555899. bioRxiv. 2023. PMID: 37693415 Free PMC article. Preprint.
A new tool to probe SARS-CoV-2 variants.
Johnson BA, Menachery VD. Johnson BA, et al. Science. 2021 Dec 24;374(6575):1557-1558. doi: 10.1126/science.abn3781. Epub 2021 Dec 23. Science. 2021. PMID: 34941409
20 results