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HIV-1 variants are archived throughout infection and persist in the reservoir.
Brooks K, Jones BR, Dilernia DA, Wilkins DJ, Claiborne DT, McInally S, Gilmour J, Kilembe W, Joy JB, Allen SA, Brumme ZL, Hunter E. Brooks K, et al. PLoS Pathog. 2020 Jun 3;16(6):e1008378. doi: 10.1371/journal.ppat.1008378. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32492044 Free PMC article. Clinical Trial.
Genetic Diversity, Compartmentalization, and Age of HIV Proviruses Persisting in CD4+ T Cell Subsets during Long-Term Combination Antiretroviral Therapy.
Jones BR, Miller RL, Kinloch NN, Tsai O, Rigsby H, Sudderuddin H, Shahid A, Ganase B, Brumme CJ, Harris M, Poon AFY, Brockman MA, Fromentin R, Chomont N, Joy JB, Brumme ZL. Jones BR, et al. J Virol. 2020 Feb 14;94(5):e01786-19. doi: 10.1128/JVI.01786-19. Print 2020 Feb 14. J Virol. 2020. PMID: 31776273 Free PMC article.