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Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.
Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, Laufman O, Tassetto M, Shales M, Stevenson E, Iglesias GN, Shokat L, Tripathi S, Balasubramaniam V, Webb LG, Aguirre S, Willsey AJ, Garcia-Sastre A, Pollard KS, Cherry S, Gamarnik AV, Marazzi I, Taunton J, Fernandez-Sesma A, Bellen HJ, Andino R, Krogan NJ. Shah PS, et al. Cell. 2018 Dec 13;175(7):1931-1945.e18. doi: 10.1016/j.cell.2018.11.028. Cell. 2018. PMID: 30550790 Free PMC article.
Antagonism of type I interferon by flaviviruses.
Miorin L, Maestre AM, Fernandez-Sesma A, García-Sastre A. Miorin L, et al. Biochem Biophys Res Commun. 2017 Oct 28;492(4):587-596. doi: 10.1016/j.bbrc.2017.05.146. Epub 2017 May 31. Biochem Biophys Res Commun. 2017. PMID: 28576494 Free PMC article. Review.
Dengue virus genomic variation associated with mosquito adaptation defines the pattern of viral non-coding RNAs and fitness in human cells.
Filomatori CV, Carballeda JM, Villordo SM, Aguirre S, Pallarés HM, Maestre AM, Sánchez-Vargas I, Blair CD, Fabri C, Morales MA, Fernandez-Sesma A, Gamarnik AV. Filomatori CV, et al. PLoS Pathog. 2017 Mar 6;13(3):e1006265. doi: 10.1371/journal.ppat.1006265. eCollection 2017 Mar. PLoS Pathog. 2017. PMID: 28264033 Free PMC article.
Aedes aegypti (Aag2)-derived clonal mosquito cell lines reveal the effects of pre-existing persistent infection with the insect-specific bunyavirus Phasi Charoen-like virus on arbovirus replication.
Fredericks AC, Russell TA, Wallace LE, Davidson AD, Fernandez-Sesma A, Maringer K. Fredericks AC, et al. PLoS Negl Trop Dis. 2019 Nov 6;13(11):e0007346. doi: 10.1371/journal.pntd.0007346. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31693659 Free PMC article.
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.
Aguirre S, Luthra P, Sanchez-Aparicio MT, Maestre AM, Patel J, Lamothe F, Fredericks AC, Tripathi S, Zhu T, Pintado-Silva J, Webb LG, Bernal-Rubio D, Solovyov A, Greenbaum B, Simon V, Basler CF, Mulder LC, García-Sastre A, Fernandez-Sesma A. Aguirre S, et al. Nat Microbiol. 2017 Mar 27;2:17037. doi: 10.1038/nmicrobiol.2017.37. Nat Microbiol. 2017. PMID: 28346446 Free PMC article.