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Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Zhou Y, Song WM, Andhey PS, Swain A, Levy T, Miller KR, Poliani PL, Cominelli M, Grover S, Gilfillan S, Cella M, Ulland TK, Zaitsev K, Miyashita A, Ikeuchi T, Sainouchi M, Kakita A, Bennett DA, Schneider JA, Nichols MR, Beausoleil SA, Ulrich JD, Holtzman DM, Artyomov MN, Colonna M. Zhou Y, et al. Nat Med. 2020 Jan;26(1):131-142. doi: 10.1038/s41591-019-0695-9. Epub 2020 Jan 13. Nat Med. 2020. PMID: 31932797 Free PMC article.
Inflammatory mechanisms in neurodegeneration.
Nichols MR, St-Pierre MK, Wendeln AC, Makoni NJ, Gouwens LK, Garrad EC, Sohrabi M, Neher JJ, Tremblay ME, Combs CK. Nichols MR, et al. J Neurochem. 2019 Jun;149(5):562-581. doi: 10.1111/jnc.14674. Epub 2019 Mar 27. J Neurochem. 2019. PMID: 30702751 Free PMC article. Review.
Disentangling aggregation-prone proteins: a new method for isolating α-synuclein species: An Editorial Highlight for "A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α-synuclein research" on page 103.
Nichols MR. Nichols MR. J Neurochem. 2020 Apr;153(1):7-9. doi: 10.1111/jnc.14973. Epub 2020 Feb 10. J Neurochem. 2020. PMID: 32037541 Free PMC article.
The intricate biophysical puzzle of caspase-1 activation.
Makoni NJ, Nichols MR. Makoni NJ, et al. Arch Biochem Biophys. 2021 Mar 15;699:108753. doi: 10.1016/j.abb.2021.108753. Epub 2021 Jan 13. Arch Biochem Biophys. 2021. PMID: 33453207 Free PMC article. Review.