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PCSK6-mediated corin activation is essential for normal blood pressure.
Chen S, Cao P, Dong N, Peng J, Zhang C, Wang H, Zhou T, Yang J, Zhang Y, Martelli EE, Naga Prasad SV, Miller RE, Malfait AM, Zhou Y, Wu Q. Chen S, et al. Nat Med. 2015 Sep;21(9):1048-53. doi: 10.1038/nm.3920. Epub 2015 Aug 10. Nat Med. 2015. PMID: 26259032 Free PMC article.
Protease corin expression and activity in failing hearts.
Chen S, Sen S, Young D, Wang W, Moravec CS, Wu Q. Chen S, et al. Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1687-92. doi: 10.1152/ajpheart.00399.2010. Epub 2010 Aug 27. Am J Physiol Heart Circ Physiol. 2010. PMID: 20802129 Free PMC article.
Plasma soluble corin in patients with heart failure.
Dong N, Chen S, Yang J, He L, Liu P, Zheng D, Li L, Zhou Y, Ruan C, Plow E, Wu Q. Dong N, et al. Circ Heart Fail. 2010 Mar;3(2):207-11. doi: 10.1161/CIRCHEARTFAILURE.109.903849. Epub 2010 Jan 8. Circ Heart Fail. 2010. PMID: 20061521 Free PMC article.