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Page 1
Leptin signaling and circuits in puberty and fertility.
Elias CF, Purohit D. Elias CF, et al. Cell Mol Life Sci. 2013 Mar;70(5):841-62. doi: 10.1007/s00018-012-1095-1. Epub 2012 Aug 2. Cell Mol Life Sci. 2013. PMID: 22851226 Free PMC article. Review.
Leptin signaling in Kiss1 neurons arises after pubertal development.
Cravo RM, Frazao R, Perello M, Osborne-Lawrence S, Williams KW, Zigman JM, Vianna C, Elias CF. Cravo RM, et al. PLoS One. 2013;8(3):e58698. doi: 10.1371/journal.pone.0058698. Epub 2013 Mar 7. PLoS One. 2013. PMID: 23505551 Free PMC article.
FOXO1 in the ventromedial hypothalamus regulates energy balance.
Kim KW, Donato J Jr, Berglund ED, Choi YH, Kohno D, Elias CF, Depinho RA, Elmquist JK. Kim KW, et al. J Clin Invest. 2012 Jul;122(7):2578-89. doi: 10.1172/JCI62848. Epub 2012 Jun 1. J Clin Invest. 2012. PMID: 22653058 Free PMC article.
Shift in Kiss1 cell activity requires estrogen receptor α.
Frazão R, Cravo RM, Donato J Jr, Ratra DV, Clegg DJ, Elmquist JK, Zigman JM, Williams KW, Elias CF. Frazão R, et al. J Neurosci. 2013 Feb 13;33(7):2807-20. doi: 10.1523/JNEUROSCI.1610-12.2013. J Neurosci. 2013. PMID: 23407940 Free PMC article.
Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.
Donato J Jr, Cravo RM, Frazão R, Gautron L, Scott MM, Lachey J, Castro IA, Margatho LO, Lee S, Lee C, Richardson JA, Friedman J, Chua S Jr, Coppari R, Zigman JM, Elmquist JK, Elias CF. Donato J Jr, et al. J Clin Invest. 2011 Jan;121(1):355-68. doi: 10.1172/JCI45106. Epub 2010 Dec 22. J Clin Invest. 2011. PMID: 21183787 Free PMC article.