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Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function.
Nat Struct Mol Biol. 2013 Jan;20(1):46-52. doi: 10.1038/nsmb.2430. Epub 2012 Nov 25.
Nat Struct Mol Biol. 2013.
PMID: 23178454
Free PMC article.
Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers.
Ebi H, Corcoran RB, Singh A, Chen Z, Song Y, Lifshits E, Ryan DP, Meyerhardt JA, Benes C, Settleman J, Wong KK, Cantley LC, Engelman JA.
Ebi H, et al.
J Clin Invest. 2011 Nov;121(11):4311-21. doi: 10.1172/JCI57909. Epub 2011 Oct 10.
J Clin Invest. 2011.
PMID: 21985784
Free PMC article.
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