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The cannabinoid receptor 2 is critical for the host response to sepsis.
Tschöp J, Kasten KR, Nogueiras R, Goetzman HS, Cave CM, England LG, Dattilo J, Lentsch AB, Tschöp MH, Caldwell CC. Tschöp J, et al. J Immunol. 2009 Jul 1;183(1):499-505. doi: 10.4049/jimmunol.0900203. Epub 2009 Jun 12. J Immunol. 2009. PMID: 19525393 Free PMC article.
Neutrophils are significant producers of IL-10 during sepsis.
Kasten KR, Muenzer JT, Caldwell CC. Kasten KR, et al. Biochem Biophys Res Commun. 2010 Feb 26;393(1):28-31. doi: 10.1016/j.bbrc.2010.01.066. Epub 2010 Jan 25. Biochem Biophys Res Commun. 2010. PMID: 20097159 Free PMC article.