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Structure- and function-based design of Plasmodium-selective proteasome inhibitors.
Nature. 2016 Feb 11;530(7589):233-6. doi: 10.1038/nature16936.
Nature. 2016.
PMID: 26863983
Free PMC article.
Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins.
Shen A, Lupardus PJ, Gersch MM, Puri AW, Albrow VE, Garcia KC, Bogyo M.
Shen A, et al.
Nat Struct Mol Biol. 2011 Mar;18(3):364-71. doi: 10.1038/nsmb.1990. Epub 2011 Feb 13.
Nat Struct Mol Biol. 2011.
PMID: 21317893
Free PMC article.
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Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB.
Puri AW, Lupardus PJ, Deu E, Albrow VE, Garcia KC, Bogyo M, Shen A.
Puri AW, et al.
Chem Biol. 2010 Nov 24;17(11):1201-11. doi: 10.1016/j.chembiol.2010.09.011.
Chem Biol. 2010.
PMID: 21095570
Free PMC article.
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The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains.
Stolze SC, Deu E, Kaschani F, Li N, Florea BI, Richau KH, Colby T, van der Hoorn RA, Overkleeft HS, Bogyo M, Kaiser M.
Stolze SC, et al.
Chem Biol. 2012 Dec 21;19(12):1546-55. doi: 10.1016/j.chembiol.2012.09.020.
Chem Biol. 2012.
PMID: 23261598
Free PMC article.
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