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TFG regulates secretory and endosomal sorting pathways in neurons to promote their activity and maintenance.
Peotter JL, Pustova I, Lettman MM, Shatadal S, Bradberry MM, Winter-Reed AD, Charan M, Sharkey EE, Alvin JR, Bren AM, Oie AK, Chapman ER, Salamat MS, Audhya A. Peotter JL, et al. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2210649119. doi: 10.1073/pnas.2210649119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161950 Free PMC article.
Long term rescue of Alzheimer's deficits in vivo by one-time gene-editing of App C-terminus.
Aulston BD, Gimse K, Bazick HO, Kramar EA, Pizzo DP, Parra-Rivas LA, Sun J, Branes-Guerrero K, Checka N, Bagheri N, Satyadev N, Carlson-Stevermer J, Saito T, Saido TC, Audhya A, Wood MA, Zylka MJ, Saha K, Roy S. Aulston BD, et al. bioRxiv [Preprint]. 2024 Jun 9:2024.06.08.598099. doi: 10.1101/2024.06.08.598099. bioRxiv. 2024. PMID: 38895278 Free PMC article. Preprint.