R01 NS100164/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2013	1
2014	2
2015	4
2016	2
2019	2
2020	3
2021	1
2022	4
2023	3
2024	0

1

Fully Automated Radiosynthesis of [¹⁸F]mG4P027 for mGluR4 Imaging.

Moon SH, El Fakhri G, Zhang Z, Brownell AL, Wang J. Moon SH, et al. iRadiology. 2023 Jun;1(2):120-127. doi: 10.1002/ird3.25. Epub 2023 Jun 20. iRadiology. 2023. PMID: 37496513 Free PMC article.

2

Detailed radiosynthesis of [¹⁸ F]mG4P027 as a positron emission tomography radiotracer for mGluR4.

Wang J, Moon SH, Cleary MB, Shoup TM, El Fakhri G, Zhang Z, Brownell AL. Wang J, et al. J Labelled Comp Radiopharm. 2023 Feb;66(2):34-40. doi: 10.1002/jlcr.4011. Epub 2023 Jan 19. J Labelled Comp Radiopharm. 2023. PMID: 36593743 Free PMC article.

3

Improved Synthesis of the Thiophenol Precursor N-(4-Chloro-3-mercaptophenyl)picolinamide for Making the mGluR4 PET Ligand.

Wang J, Shoup TM, Brownell AL, Zhang Z. Wang J, et al. Tetrahedron. 2019 Jul 19;75(29):3917-3922. doi: 10.1016/j.tet.2019.06.010. Epub 2019 Jun 6. Tetrahedron. 2019. PMID: 32831413 Free PMC article.

4

Design, Synthesis, and Characterization of [¹⁸F]mG2P026 as a High-Contrast PET Imaging Ligand for Metabotropic Glutamate Receptor 2.

Yuan G, Dhaynaut M, Guehl NJ, Afshar S, Huynh D, Moon SH, Iyengar SM, Jain MK, Pickett JE, Kang HJ, Ondrechen MJ, El Fakhri G, Normandin MD, Brownell AL. Yuan G, et al. J Med Chem. 2022 Jul 28;65(14):9939-9954. doi: 10.1021/acs.jmedchem.2c00593. Epub 2022 Jul 8. J Med Chem. 2022. PMID: 35802702 Free PMC article.

5

Synthesis and Characterization of 5-(2-Fluoro-4-[¹¹C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2.

Yuan G, Dhaynaut M, Lan Y, Guehl NJ, Huynh D, Iyengar SM, Afshar S, Jain MK, Pickett JE, Kang HJ, Wang H, Moon SH, Ondrechen MJ, Wang C, Shoup TM, El Fakhri G, Normandin MD, Brownell AL. Yuan G, et al. J Med Chem. 2022 Feb 10;65(3):2593-2609. doi: 10.1021/acs.jmedchem.1c02004. Epub 2022 Jan 28. J Med Chem. 2022. PMID: 35089713 Free PMC article.

6

Synthesis and Characterization of Fluorine-18-Labeled N-(4-Chloro-3-((fluoromethyl-d₂)thio)phenyl)picolinamide for Imaging of mGluR4 in Brain.

Wang J, Qu X, Shoup TM, Yuan G, Afshar S, Pan C, Zhu A, Choi JK, Kang HJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Wang J, et al. J Med Chem. 2020 Mar 26;63(6):3381-3389. doi: 10.1021/acs.jmedchem.0c00201. Epub 2020 Mar 4. J Med Chem. 2020. PMID: 32081008 Free PMC article.

7

Organomediated cleavage of benzoyl group enables an efficient synthesis of 1-(6-nitropyridin-2-yl)thiourea and its application for developing ¹⁸F-labeled PET tracers.

Wang J, Takahashi K, Shoup TM, Gong L, Li Y, El Fakhri G, Zhang Z, Brownell AL. Wang J, et al. Bioorg Chem. 2022 Jul;124:105804. doi: 10.1016/j.bioorg.2022.105804. Epub 2022 Apr 12. Bioorg Chem. 2022. PMID: 35468416 Free PMC article.

8

Transition Metal-Free Intermolecular C(sp²)-H Direct Amination of Furanones via a Redox Pathway.

Wei Q, Wang J, Akam EA, Yin D, Ge Z, Cheng T, Wang X, Brownell AL, Li R. Wei Q, et al. J Org Chem. 2019 Feb 1;84(3):1310-1319. doi: 10.1021/acs.joc.8b02760. Epub 2019 Jan 15. J Org Chem. 2019. PMID: 30607949

9

Synthesis and evaluation of N-(methylthiophenyl)picolinamide derivatives as PET radioligands for metabotropic glutamate receptor subtype 4.

Kil KE, Poutiainen P, Zhang Z, Zhu A, Kuruppu D, Prabhakar S, Choi JK, Tannous BA, Brownell AL. Kil KE, et al. Bioorg Med Chem Lett. 2016 Jan 1;26(1):133-9. doi: 10.1016/j.bmcl.2015.11.015. Epub 2015 Nov 10. Bioorg Med Chem Lett. 2016. PMID: 26602273 Free PMC article.

10

PET imaging studies to investigate functional expression of mGluR2 using [¹¹C]mG2P001.

Yuan G, Dhaynaut M, Guehl NJ, Neelamegam R, Moon SH, Qu X, Poutiainen P, Afshar S, Fakhri GE, Normandin MD, Brownell AL. Yuan G, et al. J Cereb Blood Flow Metab. 2023 Feb;43(2):296-308. doi: 10.1177/0271678X221130387. Epub 2022 Sep 28. J Cereb Blood Flow Metab. 2023. PMID: 36172629 Free PMC article.

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