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A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling.
Schreiber JA, Möller M, Zaydman M, Zhao L, Beller Z, Becker S, Ritter N, Hou P, Shi J, Silva J, Wrobel E, Strutz-Seebohm N, Decher N, Schmitt N, Meuth SG, Düfer M, Wünsch B, Cui J, Seebohm G. Schreiber JA, et al. Commun Biol. 2022 Apr 1;5(1):301. doi: 10.1038/s42003-022-03229-8. Commun Biol. 2022. PMID: 35365746 Free PMC article.
Arrhythmia-associated Calmodulin Variants Interact with KCNQ1 to Confer Aberrant Membrane Trafficking and Function.
Kang PW, Woodbury L, Angsutararux P, Sambare N, Shi J, Marras M, Abella C, Bedi A, Zinn D, Cui J, Silva JR. Kang PW, et al. bioRxiv [Preprint]. 2023 Jan 29:2023.01.28.526031. doi: 10.1101/2023.01.28.526031. bioRxiv. 2023. Update in: PNAS Nexus. 2023 Oct 14;2(11):pgad335. doi: 10.1093/pnasnexus/pgad335 PMID: 36747728 Free PMC article. Updated. Preprint.
13 results