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FXTAS: a bad RNA and a hope for a cure.
Shan G, Xu S, Jin P. Shan G, et al. Expert Opin Biol Ther. 2008 Mar;8(3):249-53. doi: 10.1517/14712598.8.3.249. Expert Opin Biol Ther. 2008. PMID: 18294097 Free PMC article. Review.
A small molecule enhances RNA interference and promotes microRNA processing.
Shan G, Li Y, Zhang J, Li W, Szulwach KE, Duan R, Faghihi MA, Khalil AM, Lu L, Paroo Z, Chan AW, Shi Z, Liu Q, Wahlestedt C, He C, Jin P. Shan G, et al. Nat Biotechnol. 2008 Aug;26(8):933-40. doi: 10.1038/nbt.1481. Epub 2008 Jul 20. Nat Biotechnol. 2008. PMID: 18641635 Free PMC article.