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Page 1
Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis.
Jourdon A, Wu F, Mariani J, Capauto D, Norton S, Tomasini L, Amiri A, Suvakov M, Schreiner JD, Jang Y, Panda A, Nguyen CK, Cummings EM, Han G, Powell K, Szekely A, McPartland JC, Pelphrey K, Chawarska K, Ventola P, Abyzov A, Vaccarino FM. Jourdon A, et al. Nat Neurosci. 2023 Sep;26(9):1505-1515. doi: 10.1038/s41593-023-01399-0. Epub 2023 Aug 10. Nat Neurosci. 2023. PMID: 37563294 Free PMC article.
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability.
Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, Roberts RC, Huttner A, Kleinman JE, Hyde TM, Straub RE, Walsh CA; Brain Somatic Mosaicism Network§; Urban AE, Leckman JF, Weinberger DR, Vaccarino FM, Abyzov A. Bae T, et al. Science. 2022 Jul 29;377(6605):511-517. doi: 10.1126/science.abm6222. Epub 2022 Jul 28. Science. 2022. PMID: 35901164 Free PMC article.
The use of stem cells to study autism spectrum disorder.
Ardhanareeswaran K, Coppola G, Vaccarino F. Ardhanareeswaran K, et al. Yale J Biol Med. 2015 Mar 4;88(1):5-16. eCollection 2015 Mar. Yale J Biol Med. 2015. PMID: 25745370 Free PMC article. Review.
Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data.
Dai R, Chu T, Zhang M, Wang X, Jourdon A, Wu F, Mariani J, Vaccarino FM, Lee D, Fullard JF, Hoffman GE, Roussos P, Wang Y, Wang X, Pinto D, Wang SH, Zhang C; PsychENCODE consortium; Chen C, Liu C. Dai R, et al. Sci Adv. 2024 May 24;10(21):eadh2588. doi: 10.1126/sciadv.adh2588. Epub 2024 May 23. Sci Adv. 2024. PMID: 38781336 Free PMC article.
Characterization of enhancer activity in early human neurodevelopment using Massively parallel reporter assay (MPRA) and forebrain organoids.
Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, Crawford GE; PsychENCODE Consortium; Ahituv N, Abyzov A, Vaccarino FM. Capauto D, et al. bioRxiv [Preprint]. 2023 Aug 14:2023.08.14.553170. doi: 10.1101/2023.08.14.553170. bioRxiv. 2023. Update in: Sci Rep. 2024 Feb 16;14(1):3936. doi: 10.1038/s41598-024-54302-7 PMID: 37645832 Free PMC article. Updated. Preprint.
Clonally Selected Lines After CRISPR-Cas Editing Are Not Isogenic.
Panda A, Suvakov M, Mariani J, Drucker KL, Park Y, Jang Y, Kollmeyer TM, Sarkar G, Bae T, Kim JJ, Yoon WH, Jenkins RB, Vaccarino FM, Abyzov A. Panda A, et al. CRISPR J. 2023 Apr;6(2):176-182. doi: 10.1089/crispr.2022.0050. CRISPR J. 2023. PMID: 37071670 Free PMC article.
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