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Emerging therapeutic targets for cardiac hypertrophy.
Winkle AJ, Nassal DM, Shaheen R, Thomas E, Mohta S, Gratz D, Weinberg SH, Hund TJ. Winkle AJ, et al. Expert Opin Ther Targets. 2022 Jan;26(1):29-40. doi: 10.1080/14728222.2022.2031974. Epub 2022 Jan 27. Expert Opin Ther Targets. 2022. PMID: 35076342 Free PMC article. Review.
CLIC4 localizes to mitochondrial-associated membranes and mediates cardioprotection.
Ponnalagu D, Hamilton S, Sanghvi S, Antelo D, Schwieterman N, Hansra I, Xu X, Gao E, Edwards JC, Bansal SS, Wold LE, Terentyev D, Janssen PML, Hund TJ, Khan M, Kohut AR, Koch WJ, Singh H. Ponnalagu D, et al. Sci Adv. 2022 Oct 21;8(42):eabo1244. doi: 10.1126/sciadv.abo1244. Epub 2022 Oct 21. Sci Adv. 2022. PMID: 36269835 Free PMC article.
Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant.
Wallace MJ, Malhotra N, Mariángelo JIE, Stevens TL, Young LJ, Antwi-Boasiako S, Abdallah D, Takenaka SS, Cavus O, Murphy NP, Han M, Xu X, Mangoni ME, Hund TJ, Roberts JD, Györke S, Mohler PJ, El Refaey M. Wallace MJ, et al. J Biol Chem. 2023 Jun;299(6):104818. doi: 10.1016/j.jbc.2023.104818. Epub 2023 May 12. J Biol Chem. 2023. PMID: 37182735 Free PMC article.
Empagliflozin Inhibits Cardiac Late Sodium Current by Ca/Calmodulin-Dependent Kinase II.
Mustroph J, Baier MJ, Pabel S, Stehle T, Trum M, Provaznik Z, Mohler PJ, Musa H, Hund TJ, Sossalla S, Maier LS, Wagner S. Mustroph J, et al. Circulation. 2022 Oct 18;146(16):1259-1261. doi: 10.1161/CIRCULATIONAHA.122.057364. Epub 2022 Oct 17. Circulation. 2022. PMID: 36251785 Free PMC article. No abstract available.
Cardiac-Specific Deletion of Scn8a Mitigates Dravet Syndrome-Associated Sudden Death in Adults.
King DR, Demirtas M, Tarasov M, Struckman HL, Meng X, Nassal D, Moise N, Miller A, Min D, Soltisz AM, Anne MNK, Alves Dias PA, Wagnon JL, Weinberg SH, Hund TJ, Veeraraghavan R, Radwański PB. King DR, et al. JACC Clin Electrophysiol. 2024 May;10(5):829-842. doi: 10.1016/j.jacep.2024.01.003. Epub 2024 Feb 28. JACC Clin Electrophysiol. 2024. PMID: 38430092 Free PMC article.
15 results