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Page 1
A transcriptional switch governs fibroblast activation in heart disease.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. Alexanian M, et al. Nature. 2021 Jul;595(7867):438-443. doi: 10.1038/s41586-021-03674-1. Epub 2021 Jun 23. Nature. 2021. PMID: 34163071 Free PMC article.
Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Pelonero A, Lee CY, Sadagopan N, Huang Y, Auclair K, Zhu A, An Y, Ekstrand CA, Martinez C, Teran BG, Flanigan WR, Kim CK, Lumbao-Conradson K, Gardner Z, Li L, Costa MW, Jain R, Charo I, Combes AJ, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Nature. 2024 Nov;635(8038):434-443. doi: 10.1038/s41586-024-08085-6. Epub 2024 Oct 23. Nature. 2024. PMID: 39443808
HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Travers JG, Wennersten SA, Peña B, Bagchi RA, Smith HE, Hirsch RA, Vanderlinden LA, Lin YH, Dobrinskikh E, Demos-Davies KM, Cavasin MA, Mestroni L, Steinkühler C, Lin CY, Houser SR, Woulfe KC, Lam MPY, McKinsey TA. Travers JG, et al. Circulation. 2021 May 11;143(19):1874-1890. doi: 10.1161/CIRCULATIONAHA.120.046462. Epub 2021 Mar 8. Circulation. 2021. PMID: 33682427 Free PMC article.
How Chromatin Stiffens Fibroblasts.
Hu S, Vondriska TM. Hu S, et al. Curr Opin Physiol. 2022 Apr;26:100537. doi: 10.1016/j.cophys.2022.100537. Epub 2022 Apr 12. Curr Opin Physiol. 2022. PMID: 35979086 Free PMC article.
Fat-to-heart crosstalk in health and disease.
Lodewijks F, McKinsey TA, Robinson EL. Lodewijks F, et al. Front Genet. 2023 Mar 24;14:990155. doi: 10.3389/fgene.2023.990155. eCollection 2023. Front Genet. 2023. PMID: 37035745 Free PMC article. Review.
Troponin I Tyrosine Phosphorylation Beneficially Accelerates Diastolic Function.
Salyer LG, Salhi HE, Brundage EA, Shettigar V, Sturgill SL, Zanella H, Templeton B, Abay E, Emmer KM, Lowe J, Rafael-Fortney JA, Parinandi N, Foster DB, McKinsey TA, Woulfe KC, Ziolo MT, Biesiadecki BJ. Salyer LG, et al. Circ Res. 2024 Jan 5;134(1):33-45. doi: 10.1161/CIRCRESAHA.123.323132. Epub 2023 Dec 14. Circ Res. 2024. PMID: 38095088 Free article.
Cat-apulting Toward a Molecular Understanding of HFpEF.
Robinson EL, McKinsey TA. Robinson EL, et al. JACC Basic Transl Sci. 2021 Aug 23;6(8):673-675. doi: 10.1016/j.jacbts.2021.07.005. eCollection 2021 Aug. JACC Basic Transl Sci. 2021. PMID: 34466753 Free PMC article.
27 results