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Page 1
Macrophages in atherosclerosis: a dynamic balance.
Moore KJ, Sheedy FJ, Fisher EA. Moore KJ, et al. Nat Rev Immunol. 2013 Oct;13(10):709-21. doi: 10.1038/nri3520. Epub 2013 Sep 2. Nat Rev Immunol. 2013. PMID: 23995626 Free PMC article. Review.
Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis.
Westerterp M, Fotakis P, Ouimet M, Bochem AE, Zhang H, Molusky MM, Wang W, Abramowicz S, la Bastide-van Gemert S, Wang N, Welch CL, Reilly MP, Stroes ES, Moore KJ, Tall AR. Westerterp M, et al. Circulation. 2018 Aug 28;138(9):898-912. doi: 10.1161/CIRCULATIONAHA.117.032636. Circulation. 2018. PMID: 29588315 Free PMC article.
Emerging Roles of PCSK9: More Than a One-Trick Pony.
Moore KJ, Goldberg IJ. Moore KJ, et al. Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):211-2. doi: 10.1161/ATVBAHA.115.306756. Arterioscler Thromb Vasc Biol. 2016. PMID: 26819460 Free PMC article. No abstract available.
High-density lipoproteins put out the fire.
Moore KJ, Fisher EA. Moore KJ, et al. Cell Metab. 2014 Feb 4;19(2):175-6. doi: 10.1016/j.cmet.2014.01.009. Cell Metab. 2014. PMID: 24506861 Free PMC article.
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Sheedy FJ, Grebe A, Rayner KJ, Kalantari P, Ramkhelawon B, Carpenter SB, Becker CE, Ediriweera HN, Mullick AE, Golenbock DT, Stuart LM, Latz E, Fitzgerald KA, Moore KJ. Sheedy FJ, et al. Nat Immunol. 2013 Aug;14(8):812-20. doi: 10.1038/ni.2639. Epub 2013 Jun 30. Nat Immunol. 2013. PMID: 23812099 Free PMC article.
Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype.
Vengrenyuk Y, Nishi H, Long X, Ouimet M, Savji N, Martinez FO, Cassella CP, Moore KJ, Ramsey SA, Miano JM, Fisher EA. Vengrenyuk Y, et al. Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):535-46. doi: 10.1161/ATVBAHA.114.304029. Epub 2015 Jan 8. Arterioscler Thromb Vasc Biol. 2015. PMID: 25573853 Free PMC article.