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Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.
Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe J. Heo KS, et al. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):321-9. doi: 10.1161/ATVBAHA.112.300619. Epub 2012 Nov 29. Arterioscler Thromb Vasc Biol. 2013. PMID: 23202365 Free PMC article.
The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation in endothelial cells.
Akaike M, Che W, Marmarosh NL, Ohta S, Osawa M, Ding B, Berk BC, Yan C, Abe J. Akaike M, et al. Mol Cell Biol. 2004 Oct;24(19):8691-704. doi: 10.1128/MCB.24.19.8691-8704.2004. Mol Cell Biol. 2004. PMID: 15367687 Free PMC article.