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PYK2/PDZ-RhoGEF links Ca2+ signaling to RhoA.
Ying Z, Giachini FR, Tostes RC, Webb RC. Ying Z, et al. Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1657-63. doi: 10.1161/ATVBAHA.109.190892. Arterioscler Thromb Vasc Biol. 2009. PMID: 19759375 Free PMC article.
TNF-alpha knockout mice have increased corpora cavernosa relaxation.
Carneiro FS, Sturgis LC, Giachini FR, Carneiro ZN, Lima VV, Wynne BM, San Martin S, Brands MW, Tostes RC, Webb RC. Carneiro FS, et al. J Sex Med. 2009 Jan;6(1):115-25. doi: 10.1111/j.1743-6109.2008.01029.x. J Sex Med. 2009. PMID: 19170842 Free PMC article.
TNF-alpha infusion impairs corpora cavernosa reactivity.
Carneiro FS, Zemse S, Giachini FR, Carneiro ZN, Lima VV, Webb RC, Tostes RC. Carneiro FS, et al. J Sex Med. 2009 Mar;6 Suppl 3(Suppl 3):311-9. doi: 10.1111/j.1743-6109.2008.01189.x. J Sex Med. 2009. PMID: 19267854 Free PMC article.