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The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages.
Misra UK, Kaczowka S, Pizzo SV. Misra UK, et al. Cell Signal. 2008 Aug;20(8):1459-70. doi: 10.1016/j.cellsig.2008.04.002. Epub 2008 Apr 15. Cell Signal. 2008. PMID: 18495429 Free PMC article.
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