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Psychological stress exacerbates primary vaginal herpes simplex virus type 1 (HSV-1) infection by impairing both innate and adaptive immune responses.
Brain Behav Immun. 2008 Nov;22(8):1231-40. doi: 10.1016/j.bbi.2008.06.008. Epub 2008 Jun 27.
Brain Behav Immun. 2008.
PMID: 18639627
Free PMC article.
Psychological stress impairs the local CD8+ T cell response to mucosal HSV-1 infection and allows for increased pathogenicity via a glucocorticoid receptor-mediated mechanism.
Ashcraft KA, Hunzeker J, Bonneau RH.
Ashcraft KA, et al.
Psychoneuroendocrinology. 2008 Aug;33(7):951-63. doi: 10.1016/j.psyneuen.2008.04.010. Epub 2008 Jul 25.
Psychoneuroendocrinology. 2008.
PMID: 18657369
Free PMC article.
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Elevated maternal corticosterone during lactation hinders the neonatal adaptive immune response to herpes simplex virus (HSV) infection.
Zahwa H, Yorty JL, Bonneau RH.
Zahwa H, et al.
Brain Behav Immun. 2008 Mar;22(3):339-53. doi: 10.1016/j.bbi.2007.08.012. Epub 2007 Oct 22.
Brain Behav Immun. 2008.
PMID: 17950573
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