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Page 1
Structural basis for self-discrimination by neoantigen-specific TCRs.
Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Finnigan JP, et al. Nat Commun. 2024 Mar 8;15(1):2140. doi: 10.1038/s41467-024-46367-9. Nat Commun. 2024. PMID: 38459027 Free PMC article.
Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Patskovsky Y, Natarajan A, Patskovska L, Nyovanie S, Joshi B, Morin B, Brittsan C, Huber O, Gordon S, Michelet X, Schmitzberger F, Stein RB, Findeis MA, Hurwitz A, Van Dijk M, Chantzoura E, Yague AS, Pollack Smith D, Buell JS, Underwood D, Krogsgaard M. Patskovsky Y, et al. Nat Commun. 2023 Jun 23;14(1):3763. doi: 10.1038/s41467-023-39425-1. Nat Commun. 2023. PMID: 37353482 Free PMC article.
From cellular to molecular mechanobiology.
Zhu C, Lee CY, McIntire LV. Zhu C, et al. APL Bioeng. 2020 Feb 14;4(1):010902. doi: 10.1063/1.5129937. eCollection 2020 Mar. APL Bioeng. 2020. PMID: 32095735 Free PMC article.
Dynamic bonds and their roles in mechanosensing.
Zhu C, Chen Y, Ju LA. Zhu C, et al. Curr Opin Chem Biol. 2019 Dec;53:88-97. doi: 10.1016/j.cbpa.2019.08.005. Epub 2019 Sep 27. Curr Opin Chem Biol. 2019. PMID: 31563813 Free PMC article. Review.
In situ cell-surface conformation of the TCR-CD3 signaling complex.
Natarajan A, Velmurugu Y, Becerra Flores M, Dibba F, Beesam S, Kikvadze S, Wang X, Wang W, Li T, Shin HW, Cardozo T, Krogsgaard M. Natarajan A, et al. EMBO Rep. 2024 Dec;25(12):5719-5742. doi: 10.1038/s44319-024-00314-3. Epub 2024 Nov 7. EMBO Rep. 2024. PMID: 39511422 Free PMC article.
A Conserved Allosteric Pathway in Tyrosine Kinase Regulation.
Marsiglia WM, Katigbak J, Zheng S, Mohammadi M, Zhang Y, Traaseth NJ. Marsiglia WM, et al. Structure. 2019 Aug 6;27(8):1308-1315.e3. doi: 10.1016/j.str.2019.05.002. Epub 2019 Jun 13. Structure. 2019. PMID: 31204250 Free PMC article.
Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition.
Wu P, Zhang T, Liu B, Fei P, Cui L, Qin R, Zhu H, Yao D, Martinez RJ, Hu W, An C, Zhang Y, Liu J, Shi J, Fan J, Yin W, Sun J, Zhou C, Zeng X, Xu C, Wang J, Evavold BD, Zhu C, Chen W, Lou J. Wu P, et al. Mol Cell. 2019 Mar 7;73(5):1015-1027.e7. doi: 10.1016/j.molcel.2018.12.018. Epub 2019 Jan 30. Mol Cell. 2019. PMID: 30711376 Free PMC article.