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Structure and function of prodrug-activating peptidases.
Velilla JA, Kenney GE, Gaudet R. Velilla JA, et al. Biochimie. 2023 Feb;205:124-135. doi: 10.1016/j.biochi.2022.07.019. Epub 2022 Nov 8. Biochimie. 2023. PMID: 36803695 Free PMC article. Review.
A small molecule inhibitor prevents gut bacterial genotoxin production.
Volpe MR, Velilla JA, Daniel-Ivad M, Yao JJ, Stornetta A, Villalta PW, Huang HC, Bachovchin DA, Balbo S, Gaudet R, Balskus EP. Volpe MR, et al. Nat Chem Biol. 2023 Feb;19(2):159-167. doi: 10.1038/s41589-022-01147-8. Epub 2022 Oct 17. Nat Chem Biol. 2023. PMID: 36253549 Free PMC article.
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