R01 GM102724/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2017	1
2018	2
2019	2
2020	1
2021	3
2022	2
2023	1
2025	0

1

MICU1 controls the sensitivity of the mitochondrial Ca²⁺ uniporter to activators and inhibitors.

Rodríguez-Prados M, Huang KT, Márta K, Paillard M, Csordás G, Joseph SK, Hajnóczky G. Rodríguez-Prados M, et al. Cell Chem Biol. 2023 Jun 15;30(6):606-617.e4. doi: 10.1016/j.chembiol.2023.05.002. Epub 2023 May 26. Cell Chem Biol. 2023. PMID: 37244260 Free PMC article.

2

Molecular pathophysiology of human MICU1 deficiency.

Kohlschmidt N, Elbracht M, Czech A, Häusler M, Phan V, Töpf A, Huang KT, Bartok A, Eggermann K, Zippel S, Eggermann T, Freier E, Groß C, Lochmüller H, Horvath R, Hajnóczky G, Weis J, Roos A. Kohlschmidt N, et al. Neuropathol Appl Neurobiol. 2021 Oct;47(6):840-855. doi: 10.1111/nan.12694. Epub 2021 Feb 22. Neuropathol Appl Neurobiol. 2021. PMID: 33428302

3

Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients.

Singh R, Bartok A, Paillard M, Tyburski A, Elliott M, Hajnóczky G. Singh R, et al. Sci Adv. 2022 Mar 18;8(11):eabj4716. doi: 10.1126/sciadv.abj4716. Epub 2022 Mar 18. Sci Adv. 2022. PMID: 35302860 Free PMC article.

4

IP₃ receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer.

Bartok A, Weaver D, Golenár T, Nichtova Z, Katona M, Bánsághi S, Alzayady KJ, Thomas VK, Ando H, Mikoshiba K, Joseph SK, Yule DI, Csordás G, Hajnóczky G. Bartok A, et al. Nat Commun. 2019 Aug 19;10(1):3726. doi: 10.1038/s41467-019-11646-3. Nat Commun. 2019. PMID: 31427578 Free PMC article.

5

Pharmacological inhibition of the mitochondrial Ca²⁺ uniporter: Relevance for pathophysiology and human therapy.

Márta K, Hasan P, Rodríguez-Prados M, Paillard M, Hajnóczky G. Márta K, et al. J Mol Cell Cardiol. 2021 Feb;151:135-144. doi: 10.1016/j.yjmcc.2020.09.014. Epub 2020 Oct 6. J Mol Cell Cardiol. 2021. PMID: 33035551 Free PMC article. Review.

6

MICU1 Confers Protection from MCU-Dependent Manganese Toxicity.

Wettmarshausen J, Goh V, Huang KT, Arduino DM, Tripathi U, Leimpek A, Cheng Y, Pittis AA, Gabaldón T, Mokranjac D, Hajnóczky G, Perocchi F. Wettmarshausen J, et al. Cell Rep. 2018 Nov 6;25(6):1425-1435.e7. doi: 10.1016/j.celrep.2018.10.037. Cell Rep. 2018. PMID: 30403999 Free article.

7

MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.

Antony AN, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, Rubin E, Csordás G, Seifert EL, Hoek JB, Hajnóczky G. Antony AN, et al. Nat Commun. 2016 Mar 9;7:10955. doi: 10.1038/ncomms10955. Nat Commun. 2016. PMID: 26956930 Free PMC article.

8

Dysregulation of Mitochondrial Ca²⁺ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1.

Debattisti V, Horn A, Singh R, Seifert EL, Hogarth MW, Mazala DA, Huang KT, Horvath R, Jaiswal JK, Hajnóczky G. Debattisti V, et al. Cell Rep. 2019 Oct 29;29(5):1274-1286.e6. doi: 10.1016/j.celrep.2019.09.063. Cell Rep. 2019. PMID: 31665639 Free PMC article.

9

Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca²⁺ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU.

Paillard M, Csordás G, Szanda G, Golenár T, Debattisti V, Bartok A, Wang N, Moffat C, Seifert EL, Spät A, Hajnóczky G. Paillard M, et al. Cell Rep. 2017 Mar 7;18(10):2291-2300. doi: 10.1016/j.celrep.2017.02.032. Cell Rep. 2017. PMID: 28273446 Free PMC article.

10

MICU1 Interacts with the D-Ring of the MCU Pore to Control Its Ca²⁺ Flux and Sensitivity to Ru360.

Paillard M, Csordás G, Huang KT, Várnai P, Joseph SK, Hajnóczky G. Paillard M, et al. Mol Cell. 2018 Nov 15;72(4):778-785.e3. doi: 10.1016/j.molcel.2018.09.008. Epub 2018 Oct 25. Mol Cell. 2018. PMID: 30454562 Free PMC article.

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