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Page 1
Molecular Mechanism of Pin1-Tau Recognition and Catalysis.
Eichner T, Kutter S, Labeikovsky W, Buosi V, Kern D. Eichner T, et al. J Mol Biol. 2016 May 8;428(9 Pt A):1760-75. doi: 10.1016/j.jmb.2016.03.009. Epub 2016 Mar 17. J Mol Biol. 2016. PMID: 26996941
The energy landscape of adenylate kinase during catalysis.
Kerns SJ, Agafonov RV, Cho YJ, Pontiggia F, Otten R, Pachov DV, Kutter S, Phung LA, Murphy PN, Thai V, Alber T, Hagan MF, Kern D. Kerns SJ, et al. Nat Struct Mol Biol. 2015 Feb;22(2):124-31. doi: 10.1038/nsmb.2941. Epub 2015 Jan 12. Nat Struct Mol Biol. 2015. PMID: 25580578 Free PMC article.
Evolutionary drivers of thermoadaptation in enzyme catalysis.
Nguyen V, Wilson C, Hoemberger M, Stiller JB, Agafonov RV, Kutter S, English J, Theobald DL, Kern D. Nguyen V, et al. Science. 2017 Jan 20;355(6322):289-294. doi: 10.1126/science.aah3717. Epub 2016 Dec 22. Science. 2017. PMID: 28008087 Free PMC article.
Ancient origins of allosteric activation in a Ser-Thr kinase.
Hadzipasic A, Wilson C, Nguyen V, Kern N, Kim C, Pitsawong W, Villali J, Zheng Y, Kern D. Hadzipasic A, et al. Science. 2020 Feb 21;367(6480):912-917. doi: 10.1126/science.aay9959. Science. 2020. PMID: 32079772 Free PMC article.
Evolution and intelligent design in drug development.
Agafonov RV, Wilson C, Kern D. Agafonov RV, et al. Front Mol Biosci. 2015 May 21;2:27. doi: 10.3389/fmolb.2015.00027. eCollection 2015. Front Mol Biosci. 2015. PMID: 26052517 Free PMC article.
17 results