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Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells.
Stadler SC, Vincent CT, Fedorov VD, Patsialou A, Cherrington BD, Wakshlag JJ, Mohanan S, Zee BM, Zhang X, Garcia BA, Condeelis JS, Brown AM, Coonrod SA, Allis CD. Stadler SC, et al. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11851-6. doi: 10.1073/pnas.1308362110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818587 Free PMC article.
H3R42me2a is a histone modification with positive transcriptional effects.
Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD. Casadio F, et al. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14894-9. doi: 10.1073/pnas.1312925110. Epub 2013 Aug 26. Proc Natl Acad Sci U S A. 2013. PMID: 23980157 Free PMC article.