R01 GM067946/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2007	1
2008	2
2010	3
2011	5
2012	3
2013	1
2014	3
2015	1
2016	1
2019	1
2021	1
2024	0

1

PHLPPing through history: a decade in the life of PHLPP phosphatases.

Grzechnik AT, Newton AC. Grzechnik AT, et al. Biochem Soc Trans. 2016 Dec 15;44(6):1675-1682. doi: 10.1042/BST20160170. Biochem Soc Trans. 2016. PMID: 27913677 Free PMC article. Review.

2

Turning off AKT: PHLPP as a drug target.

Newton AC, Trotman LC. Newton AC, et al. Annu Rev Pharmacol Toxicol. 2014;54:537-58. doi: 10.1146/annurev-pharmtox-011112-140338. Annu Rev Pharmacol Toxicol. 2014. PMID: 24392697 Free PMC article. Review.

3

PHLPP1 counter-regulates STAT1-mediated inflammatory signaling.

Cohen Katsenelson K, Stender JD, Kawashima AT, Lordén G, Uchiyama S, Nizet V, Glass CK, Newton AC. Cohen Katsenelson K, et al. Elife. 2019 Aug 13;8:e48609. doi: 10.7554/eLife.48609. Elife. 2019. PMID: 31408005 Free PMC article.

4

PHLiPPing the switch on Akt and protein kinase C signaling.

Brognard J, Newton AC. Brognard J, et al. Trends Endocrinol Metab. 2008 Aug;19(6):223-30. doi: 10.1016/j.tem.2008.04.001. Epub 2008 May 27. Trends Endocrinol Metab. 2008. PMID: 18511290 Free PMC article. Review.

5

Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling.

Warfel NA, Newton AC. Warfel NA, et al. J Biol Chem. 2012 Feb 3;287(6):3610-6. doi: 10.1074/jbc.R111.318675. Epub 2011 Dec 5. J Biol Chem. 2012. PMID: 22144674 Free PMC article.

6

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

Kawashima AT, Wong C, Lordén G, King CC, Lara-Gonzalez P, Desai A, Gingras AC, Newton AC. Kawashima AT, et al. Mol Cell Biol. 2021 Feb 23;41(3):e0033320. doi: 10.1128/MCB.00333-20. Epub 2021 Jan 4. Mol Cell Biol. 2021. PMID: 33397691 Free PMC article.

7

Suppression of survival signalling pathways by the phosphatase PHLPP.

O'Neill AK, Niederst MJ, Newton AC. O'Neill AK, et al. FEBS J. 2013 Jan;280(2):572-83. doi: 10.1111/j.1742-4658.2012.08537.x. Epub 2012 Mar 16. FEBS J. 2013. PMID: 22340730 Free PMC article.

8

Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells.

Patterson SJ, Han JM, Garcia R, Assi K, Gao T, O'Neill A, Newton AC, Levings MK. Patterson SJ, et al. J Immunol. 2011 May 15;186(10):5533-7. doi: 10.4049/jimmunol.1002126. Epub 2011 Apr 15. J Immunol. 2011. PMID: 21498666 Free PMC article.

9

PHLPP-1 negatively regulates Akt activity and survival in the heart.

Miyamoto S, Purcell NH, Smith JM, Gao T, Whittaker R, Huang K, Castillo R, Glembotski CC, Sussman MA, Newton AC, Brown JH. Miyamoto S, et al. Circ Res. 2010 Aug 20;107(4):476-84. doi: 10.1161/CIRCRESAHA.109.215020. Epub 2010 Jun 24. Circ Res. 2010. PMID: 20576936 Free PMC article.

10

The phosphatase PHLPP controls the cellular levels of protein kinase C.

Gao T, Brognard J, Newton AC. Gao T, et al. J Biol Chem. 2008 Mar 7;283(10):6300-11. doi: 10.1074/jbc.M707319200. Epub 2007 Dec 27. J Biol Chem. 2008. PMID: 18162466 Free article.

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