R01 GM067113/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2005	1
2006	1
2008	4
2009	3
2010	4
2011	7
2012	3
2014	4
2015	6
2016	7
2017	2
2018	5
2019	2
2020	1
2021	1
2022	1
2024	0

1

Advancing targeted protein degradation for cancer therapy.

Dale B, Cheng M, Park KS, Kaniskan HÜ, Xiong Y, Jin J. Dale B, et al. Nat Rev Cancer. 2021 Oct;21(10):638-654. doi: 10.1038/s41568-021-00365-x. Epub 2021 Jun 15. Nat Rev Cancer. 2021. PMID: 34131295 Free PMC article. Review.

2

SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.

Chen XF, Tian MX, Sun RQ, Zhang ML, Zhou LS, Jin L, Chen LL, Zhou WJ, Duan KL, Chen YJ, Gao C, Cheng ZL, Wang F, Zhang JY, Sun YP, Yu HX, Zhao YZ, Yang Y, Liu WR, Shi YH, Xiong Y, Guan KL, Ye D. Chen XF, et al. EMBO Rep. 2018 May;19(5):e45124. doi: 10.15252/embr.201745124. Epub 2018 Feb 28. EMBO Rep. 2018. PMID: 29491006 Free PMC article.

3

CRL4s: the CUL4-RING E3 ubiquitin ligases.

Jackson S, Xiong Y. Jackson S, et al. Trends Biochem Sci. 2009 Nov;34(11):562-70. doi: 10.1016/j.tibs.2009.07.002. Epub 2009 Oct 7. Trends Biochem Sci. 2009. PMID: 19818632 Free PMC article. Review.

4

CRL4^DCAF1/VprBP E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development.

Han XR, Sasaki N, Jackson SC, Wang P, Li Z, Smith MD, Xie L, Chen X, Zhang Y, Marzluff WF, Xiong Y. Han XR, et al. Sci Adv. 2020 Dec 18;6(51):eabd6078. doi: 10.1126/sciadv.abd6078. Print 2020 Dec. Sci Adv. 2020. PMID: 33355139 Free PMC article.

5

Chromatin regulation by CRL4 E3 ubiquitin ligases: CUL4B targets WDR5 ubiquitylation in the nucleus.

Nakagawa T, Xiong Y. Nakagawa T, et al. Cell Cycle. 2011 Dec 15;10(24):4197-8. doi: 10.4161/cc.10.24.18407. Epub 2011 Dec 15. Cell Cycle. 2011. PMID: 22107965 Free PMC article. No abstract available.

6

DCAF1 controls T-cell function via p53-dependent and -independent mechanisms.

Guo Z, Kong Q, Liu C, Zhang S, Zou L, Yan F, Whitmire JK, Xiong Y, Chen X, Wan YY. Guo Z, et al. Nat Commun. 2016 Jan 5;7:10307. doi: 10.1038/ncomms10307. Nat Commun. 2016. PMID: 26728942 Free PMC article.

7

Targeting p21 degradation locally.

Xiong Y. Xiong Y. Dev Cell. 2010 Nov 16;19(5):641-3. doi: 10.1016/j.devcel.2010.10.020. Dev Cell. 2010. PMID: 21074711 Free PMC article.

8

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

Wang P, Yan F, Li Z, Yu Y, Parnell SE, Xiong Y. Wang P, et al. J Clin Invest. 2019 Jul 25;129(10):4393-4407. doi: 10.1172/JCI129107. J Clin Invest. 2019. PMID: 31343991 Free PMC article.

9

L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration.

Ma S, Sun R, Jiang B, Gao J, Deng W, Liu P, He R, Cui J, Ji M, Yi W, Yang P, Wu X, Xiong Y, Qiu Z, Ye D, Guan KL. Ma S, et al. Mol Cell Biol. 2017 Mar 31;37(8):e00492-16. doi: 10.1128/MCB.00492-16. Print 2017 Apr 15. Mol Cell Biol. 2017. PMID: 28137912 Free PMC article.

10

Endothelin Promotes Colorectal Tumorigenesis by Activating YAP/TAZ.

Wang Z, Liu P, Zhou X, Wang T, Feng X, Sun YP, Xiong Y, Yuan HX, Guan KL. Wang Z, et al. Cancer Res. 2017 May 1;77(9):2413-2423. doi: 10.1158/0008-5472.CAN-16-3229. Epub 2017 Mar 1. Cancer Res. 2017. PMID: 28249901 Free PMC article.

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