R01 GM064347/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2000	2
2002	1
2003	2
2004	2
2006	5
2007	1
2008	4
2009	4
2010	6
2011	3
2012	3
2013	1
2014	1
2015	3
2017	1
2019	1
2020	1
2025	0

1

Anderson J, Schiffer C, Lee SK, Swanstrom R. Anderson J, et al. Handb Exp Pharmacol. 2009;189(189):85-110. doi: 10.1007/978-3-540-79086-0_4. Handb Exp Pharmacol. 2009. PMID: 19048198 Free PMC article. Review.

2

Characterizing Protein-Ligand Binding Using Atomistic Simulation and Machine Learning: Application to Drug Resistance in HIV-1 Protease.

Whitfield TW, Ragland DA, Zeldovich KB, Schiffer CA. Whitfield TW, et al. J Chem Theory Comput. 2020 Feb 11;16(2):1284-1299. doi: 10.1021/acs.jctc.9b00781. Epub 2020 Jan 16. J Chem Theory Comput. 2020. PMID: 31877249 Free PMC article.

3

Molecular Basis for Drug Resistance in HIV-1 Protease.

Ali A, Bandaranayake RM, Cai Y, King NM, Kolli M, Mittal S, Murzycki JF, Nalam MNL, Nalivaika EA, Özen A, Prabu-Jeyabalan MM, Thayer K, Schiffer CA. Ali A, et al. Viruses. 2010 Nov;2(11):2509-2535. doi: 10.3390/v2112509. Epub 2010 Nov 12. Viruses. 2010. PMID: 21994628 Free PMC article.

4

Combating susceptibility to drug resistance: lessons from HIV-1 protease.

King NM, Prabu-Jeyabalan M, Nalivaika EA, Schiffer CA. King NM, et al. Chem Biol. 2004 Oct;11(10):1333-8. doi: 10.1016/j.chembiol.2004.08.010. Chem Biol. 2004. PMID: 15489160

5

How does a symmetric dimer recognize an asymmetric substrate? A substrate complex of HIV-1 protease.

Prabu-Jeyabalan M, Nalivaika E, Schiffer CA. Prabu-Jeyabalan M, et al. J Mol Biol. 2000 Sep 1;301(5):1207-20. doi: 10.1006/jmbi.2000.4018. J Mol Biol. 2000. PMID: 10966816

6

Co-evolution of nelfinavir-resistant HIV-1 protease and the p1-p6 substrate.

Kolli M, Lastere S, Schiffer CA. Kolli M, et al. Virology. 2006 Apr 10;347(2):405-9. doi: 10.1016/j.virol.2005.11.049. Epub 2006 Jan 20. Virology. 2006. PMID: 16430939 Free article.

7

HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly.

Favard C, Chojnacki J, Merida P, Yandrapalli N, Mak J, Eggeling C, Muriaux D. Favard C, et al. Sci Adv. 2019 Oct 2;5(10):eaaw8651. doi: 10.1126/sciadv.aaw8651. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31616784 Free PMC article.

8

Substrate envelope and drug resistance: crystal structure of RO1 in complex with wild-type human immunodeficiency virus type 1 protease.

Prabu-Jeyabalan M, King NM, Nalivaika EA, Heilek-Snyder G, Cammack N, Schiffer CA. Prabu-Jeyabalan M, et al. Antimicrob Agents Chemother. 2006 Apr;50(4):1518-21. doi: 10.1128/AAC.50.4.1518-1521.2006. Antimicrob Agents Chemother. 2006. PMID: 16569872 Free PMC article.

9

A Direct Interaction with RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In Vitro.

Potempa M, Nalivaika E, Ragland D, Lee SK, Schiffer CA, Swanstrom R. Potempa M, et al. J Mol Biol. 2015 Jul 17;427(14):2360-78. doi: 10.1016/j.jmb.2015.05.007. Epub 2015 May 15. J Mol Biol. 2015. PMID: 25986307 Free PMC article.

10

HIV-1 Protease and Substrate Coevolution Validates the Substrate Envelope As the Substrate Recognition Pattern.

Ozen A, Haliloğlu T, Schiffer CA. Ozen A, et al. J Chem Theory Comput. 2012 Feb 14;8(2):10.1021/ct200668a. doi: 10.1021/ct200668a. J Chem Theory Comput. 2012. PMID: 24348205 Free PMC article.

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