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Darunavir, a conceptually new HIV-1 protease inhibitor for the treatment of drug-resistant HIV.
Bioorg Med Chem. 2007 Dec 15;15(24):7576-80. doi: 10.1016/j.bmc.2007.09.010. Epub 2007 Sep 14.
Bioorg Med Chem. 2007.
PMID: 17900913
Free PMC article.
Review.
Effectiveness of nonpeptide clinical inhibitor TMC-114 on HIV-1 protease with highly drug resistant mutations D30N, I50V, and L90M.
Kovalevsky AY, Tie Y, Liu F, Boross PI, Wang YF, Leshchenko S, Ghosh AK, Harrison RW, Weber IT.
Kovalevsky AY, et al.
J Med Chem. 2006 Feb 23;49(4):1379-87. doi: 10.1021/jm050943c.
J Med Chem. 2006.
PMID: 16480273
Free PMC article.
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