R01 GM046732/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2000	1
2003	1
2005	3
2006	2
2007	1
2008	1
2009	3
2011	1
2012	1
2013	2
2015	1
2016	1
2023	1
2025	0

1

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers.

Defour JP, Leroy E, Dass S, Balligand T, Levy G, Brett IC, Papadopoulos N, Mouton C, Genet L, Pecquet C, Staerk J, Smith SO, Constantinescu SN. Defour JP, et al. Elife. 2023 Jun 20;12:e81521. doi: 10.7554/eLife.81521. Elife. 2023. PMID: 37338955 Free PMC article.

2

Transmembrane helix orientation influences membrane binding of the intracellular juxtamembrane domain in Neu receptor peptides.

Matsushita C, Tamagaki H, Miyazawa Y, Aimoto S, Smith SO, Sato T. Matsushita C, et al. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1646-51. doi: 10.1073/pnas.1215207110. Epub 2013 Jan 14. Proc Natl Acad Sci U S A. 2013. PMID: 23319611 Free PMC article.

3

EGFR juxtamembrane domain, membranes, and calmodulin: kinetics of their interaction.

Sengupta P, Bosis E, Nachliel E, Gutman M, Smith SO, Mihályné G, Zaitseva I, McLaughlin S. Sengupta P, et al. Biophys J. 2009 Jun 17;96(12):4887-95. doi: 10.1016/j.bpj.2009.03.027. Biophys J. 2009. PMID: 19527647 Free PMC article.

4

A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis.

Sato T, Tang TC, Reubins G, Fei JZ, Fujimoto T, Kienlen-Campard P, Constantinescu SN, Octave JN, Aimoto S, Smith SO. Sato T, et al. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1421-6. doi: 10.1073/pnas.0812261106. Epub 2009 Jan 21. Proc Natl Acad Sci U S A. 2009. PMID: 19164538 Free PMC article.

5

Synthesis, purification, and characterization of single helix membrane peptides and proteins for NMR spectroscopy.

Itaya M, Brett IC, Smith SO. Itaya M, et al. Methods Mol Biol. 2012;831:333-57. doi: 10.1007/978-1-61779-480-3_18. Methods Mol Biol. 2012. PMID: 22167682

6

High-resolution 1H MAS RFDR NMR of biological membranes.

Aucoin D, Camenares D, Zhao X, Jung J, Sato T, Smith SO. Aucoin D, et al. J Magn Reson. 2009 Mar;197(1):77-86. doi: 10.1016/j.jmr.2008.12.009. Epub 2008 Dec 14. J Magn Reson. 2009. PMID: 19121592 Free PMC article.

7

An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor.

Staerk J, Lacout C, Sato T, Smith SO, Vainchenker W, Constantinescu SN. Staerk J, et al. Blood. 2006 Mar 1;107(5):1864-71. doi: 10.1182/blood-2005-06-2600. Epub 2005 Oct 25. Blood. 2006. PMID: 16249382 Free PMC article.

8

Helix packing and orientation in the transmembrane dimer of gp55-P of the spleen focus forming virus.

Liu W, Crocker E, Constantinescu SN, Smith SO. Liu W, et al. Biophys J. 2005 Aug;89(2):1194-202. doi: 10.1529/biophysj.104.057844. Epub 2005 May 13. Biophys J. 2005. PMID: 15894629 Free PMC article.

9

Role of side-chain conformational entropy in transmembrane helix dimerization of glycophorin A.

Liu W, Crocker E, Siminovitch DJ, Smith SO. Liu W, et al. Biophys J. 2003 Feb;84(2 Pt 1):1263-71. doi: 10.1016/S0006-3495(03)74941-8. Biophys J. 2003. PMID: 12547806 Free PMC article.

10

Orientation-specific signalling by thrombopoietin receptor dimers.

Staerk J, Defour JP, Pecquet C, Leroy E, Antoine-Poirel H, Brett I, Itaya M, Smith SO, Vainchenker W, Constantinescu SN. Staerk J, et al. EMBO J. 2011 Sep 2;30(21):4398-413. doi: 10.1038/emboj.2011.315. EMBO J. 2011. PMID: 21892137 Free PMC article.

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