R01 GM035906-27/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

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A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.

Sasaki E, Ogasawara Y, Liu HW. Sasaki E, et al. J Am Chem Soc. 2010 Jun 2;132(21):7405-17. doi: 10.1021/ja1014037. J Am Chem Soc. 2010. PMID: 20443562 Free PMC article.

Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the methymycin/picromycin biosynthetic pathway.

Borisova SA, Liu HW. Borisova SA, et al. Biochemistry. 2010 Sep 21;49(37):8071-84. doi: 10.1021/bi1007657. Biochemistry. 2010. PMID: 20695498 Free PMC article.

Mechanistic studies of the biosynthesis of 2-thiosugar: evidence for the formation of an enzyme-bound 2-ketohexose intermediate in BexX-catalyzed reaction.

Sasaki E, Liu HW. Sasaki E, et al. J Am Chem Soc. 2010 Nov 10;132(44):15544-6. doi: 10.1021/ja108061c. J Am Chem Soc. 2010. PMID: 20961106 Free PMC article.

A de novo approach to the synthesis of glycosylated methymycin analogues with structural and stereochemical diversity.

Borisova SA, Guppi SR, Kim HJ, Wu B, Penn JH, Liu HW, O'Doherty GA. Borisova SA, et al. Org Lett. 2010 Nov 19;12(22):5150-3. doi: 10.1021/ol102144g. Epub 2010 Oct 19. Org Lett. 2010. PMID: 20958086 Free PMC article.

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