R01 ES006376-17/ES/NIEHS NIH HHS/United States[Grants and Funding] - Search Results

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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression.

Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, Osterreicher CH, Takahashi H, Karin M. Park EJ, et al. Cell. 2010 Jan 22;140(2):197-208. doi: 10.1016/j.cell.2009.12.052. Cell. 2010. PMID: 20141834 Free PMC article.

Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation.

He G, Yu GY, Temkin V, Ogata H, Kuntzen C, Sakurai T, Sieghart W, Peck-Radosavljevic M, Leffert HL, Karin M. He G, et al. Cancer Cell. 2010 Mar 16;17(3):286-97. doi: 10.1016/j.ccr.2009.12.048. Cancer Cell. 2010. PMID: 20227042 Free PMC article.

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.

Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Ellisman MH, Bodmer R, Bier E, Karin M. Lee JH, et al. Science. 2010 Mar 5;327(5970):1223-8. doi: 10.1126/science.1182228. Science. 2010. PMID: 20203043 Free PMC article.

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