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Page 1
Oncometabolites suppress DNA repair by disrupting local chromatin signalling.
Sulkowski PL, Oeck S, Dow J, Economos NG, Mirfakhraie L, Liu Y, Noronha K, Bao X, Li J, Shuch BM, King MC, Bindra RS, Glazer PM. Sulkowski PL, et al. Nature. 2020 Jun;582(7813):586-591. doi: 10.1038/s41586-020-2363-0. Epub 2020 Jun 3. Nature. 2020. PMID: 32494005 Free PMC article.
A parametric meta-analysis.
Yu C, Zelterman D. Yu C, et al. Stat Med. 2019 Sep 20;38(21):4013-4025. doi: 10.1002/sim.8278. Epub 2019 Jun 17. Stat Med. 2019. PMID: 31206759 Free PMC article.
Hypoxia and DNA repair.
Glazer PM, Hegan DC, Lu Y, Czochor J, Scanlon SE. Glazer PM, et al. Yale J Biol Med. 2013 Dec 13;86(4):443-51. Yale J Biol Med. 2013. PMID: 24348208 Free PMC article.
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.
Sulkowski PL, Corso CD, Robinson ND, Scanlon SE, Purshouse KR, Bai H, Liu Y, Sundaram RK, Hegan DC, Fons NR, Breuer GA, Song Y, Mishra-Gorur K, De Feyter HM, de Graaf RA, Surovtseva YV, Kachman M, Halene S, Günel M, Glazer PM, Bindra RS. Sulkowski PL, et al. Sci Transl Med. 2017 Feb 1;9(375):eaal2463. doi: 10.1126/scitranslmed.aal2463. Sci Transl Med. 2017. PMID: 28148839 Free PMC article.
52 results