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The cell biology of ferroptosis.
Dixon SJ, Olzmann JA. Dixon SJ, et al. Nat Rev Mol Cell Biol. 2024 Jun;25(6):424-442. doi: 10.1038/s41580-024-00703-5. Epub 2024 Feb 16. Nat Rev Mol Cell Biol. 2024. PMID: 38366038 Review.
Lipid droplets and cellular lipid flux.
Mathiowetz AJ, Olzmann JA. Mathiowetz AJ, et al. Nat Cell Biol. 2024 Mar;26(3):331-345. doi: 10.1038/s41556-024-01364-4. Epub 2024 Mar 7. Nat Cell Biol. 2024. PMID: 38454048 Review.
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.
Roberts MA, Deol KK, Mathiowetz AJ, Lange M, Leto DE, Stevenson J, Hashemi SH, Morgens DW, Easter E, Heydari K, Nalls MA, Bassik MC, Kampmann M, Kopito RR, Faghri F, Olzmann JA. Roberts MA, et al. Dev Cell. 2023 Sep 25;58(18):1782-1800.e10. doi: 10.1016/j.devcel.2023.07.001. Epub 2023 Jul 25. Dev Cell. 2023. PMID: 37494933 Free PMC article.
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.
Mathiowetz AJ, Meymand ES, Deol KK, Parlakgül G, Lange M, Pang SP, Roberts MA, Torres EF, Jorgens DM, Zalpuri R, Kang M, Boone C, Zhang Y, Morgens DW, Tso E, Zhou Y, Talukdar S, Levine TP, Ku G, Arruda AP, Olzmann JA. Mathiowetz AJ, et al. bioRxiv [Preprint]. 2024 Jun 8:2024.06.07.597858. doi: 10.1101/2024.06.07.597858. bioRxiv. 2024. PMID: 38895340 Free PMC article. Preprint.
VPS13A and VPS13C Influence Lipid Droplet Abundance.
Chen S, Roberts MA, Chen CY, Markmiller S, Wei HG, Yeo GW, Granneman JG, Olzmann JA, Ferro-Novick S. Chen S, et al. Contact (Thousand Oaks). 2022 Sep 13;5:25152564221125613. doi: 10.1177/25152564221125613. eCollection 2022 Jan-Dec. Contact (Thousand Oaks). 2022. PMID: 36147729 Free PMC article.