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Murine Models for Staphylococcal Infection.
Klopfenstein N, Cassat JE, Monteith A, Miller A, Drury S, Skaar E, Serezani CH. Klopfenstein N, et al. Curr Protoc. 2021 Mar;1(3):e52. doi: 10.1002/cpz1.52. Curr Protoc. 2021. PMID: 33656290 Free PMC article.
STAT4 is expressed in neutrophils and promotes antimicrobial immunity.
Mehrpouya-Bahrami P, Moriarty AK, De Melo P, Keeter WC, Alakhras NS, Nelson AS, Hoover M, Barrios MS, Nadler JL, Serezani CH, Kaplan MH, Galkina EV. Mehrpouya-Bahrami P, et al. JCI Insight. 2021 Jul 22;6(14):e141326. doi: 10.1172/jci.insight.141326. JCI Insight. 2021. PMID: 34138758 Free PMC article.
Leukotriene B4 licenses inflammasome activation to enhance skin host defense.
Salina ACG, Brandt SL, Klopfenstein N, Blackman A, Bazzano JMR, Sá-Nunes A, Byers-Glosson N, Brodskyn C, Tavares NM, Da Silva IBS, Medeiros AI, Serezani CH. Salina ACG, et al. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30619-30627. doi: 10.1073/pnas.2002732117. Epub 2020 Nov 12. Proc Natl Acad Sci U S A. 2020. PMID: 33184178 Free PMC article.
Prediabetes Induces More Severe Acute COVID-19 Associated With IL-6 Production Without Worsening Long-Term Symptoms.
Bonyek-Silva I, Cerqueira-Silva T, Nunes S, Machado AFA, Cruz MRS, Pereira B, Estrela L, Silva J, Isis A, Barral A, Oliveira PRS, Khouri R, Serezani CH, Brodskyn C, Caldas JR, Barral-Netto M, Boaventura V, Tavares NM. Bonyek-Silva I, et al. Front Endocrinol (Lausanne). 2022 Jul 8;13:896378. doi: 10.3389/fendo.2022.896378. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35898449 Free PMC article.
LTB4-Driven Inflammation and Increased Expression of ALOX5/ACE2 During Severe COVID-19 in Individuals With Diabetes.
Bonyek-Silva I, Machado AFA, Cerqueira-Silva T, Nunes S, Silva Cruz MR, Silva J, Santos RL, Barral A, Oliveira PRS, Khouri R, Serezani CH, Brodskyn C, Caldas JR, Barral-Netto M, Boaventura V, Tavares NM. Bonyek-Silva I, et al. Diabetes. 2021 Sep;70(9):2120-2130. doi: 10.2337/db20-1260. Epub 2021 Jun 15. Diabetes. 2021. PMID: 34417262 Free PMC article.
Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation.
Pham L, Komalavilas P, Eddie AM, Thayer TE, Greenwood DL, Liu KH, Weinberg J, Patterson A, Fessel JP, Boyd KL, Schafer JC, Kuck JL, Shaver AC, Flaherty DK, Matlock BK, Wijers CDM, Serezani CH, Jones DP, Brittain EL, Rathmell JC, Noto MJ. Pham L, et al. Commun Biol. 2022 Dec 13;5(1):1366. doi: 10.1038/s42003-022-04339-z. Commun Biol. 2022. PMID: 36513703 Free PMC article.
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