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Page 1
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S. Han Y, et al. Nature. 2021 Jan;589(7841):270-275. doi: 10.1038/s41586-020-2901-9. Epub 2020 Oct 28. Nature. 2021. PMID: 33116299 Free PMC article.
Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells.
Xue D, Narisu N, Taylor DL, Zhang M, Grenko C, Taylor HJ, Yan T, Tang X, Sinha N, Zhu J, Vandana JJ, Nok Chong AC, Lee A, Mansell EC, Swift AJ, Erdos MR, Zhong A, Bonnycastle LL, Zhou T, Chen S, Collins FS. Xue D, et al. Cell Metab. 2023 Nov 7;35(11):1897-1914.e11. doi: 10.1016/j.cmet.2023.09.013. Epub 2023 Oct 18. Cell Metab. 2023. PMID: 37858332 Free PMC article.
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, Zhang T, Kim TW, Harschnitz O, Redmond D, Houghton S, Liu C, Naji A, Ciceri G, Guttikonda S, Bram Y, Nguyen DT, Cioffi M, Chandar V, Hoagland DA, Huang Y, Xiang J, Wang H, Lyden D, Borczuk A, Chen HJ, Studer L, Pan FC, Ho DD, tenOever BR, Evans T, Schwartz RE, Chen S. Yang L, et al. Cell Stem Cell. 2020 Jul 2;27(1):125-136.e7. doi: 10.1016/j.stem.2020.06.015. Epub 2020 Jun 19. Cell Stem Cell. 2020. PMID: 32579880 Free PMC article.
Human organoid models to study SARS-CoV-2 infection.
Han Y, Yang L, Lacko LA, Chen S. Han Y, et al. Nat Methods. 2022 Apr;19(4):418-428. doi: 10.1038/s41592-022-01453-y. Epub 2022 Apr 8. Nat Methods. 2022. PMID: 35396481 Review.
Checkpoint kinase 2 controls insulin secretion and glucose homeostasis.
Chong ACN, Vandana JJ, Jeng G, Li G, Meng Z, Duan X, Zhang T, Qiu Y, Duran-Struuck R, Coker K, Wang W, Li Y, Min Z, Zuo X, de Silva N, Chen Z, Naji A, Hao M, Liu C, Chen S. Chong ACN, et al. Nat Chem Biol. 2024 May;20(5):566-576. doi: 10.1038/s41589-023-01466-4. Epub 2023 Nov 9. Nat Chem Biol. 2024. PMID: 37945898 Free PMC article.
SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence.
Han Y, Yang L, Kim TW, Nair MS, Harschnitz O, Wang P, Zhu J, Koo SY, Tang X, Lacko LA, Chandar V, Bram Y, Zhang T, Zhang W, He F, Caicedo J, Huang Y, Evans T, van der Valk P, Titulaer MJ, Spoor JKH, Furler RL, Canoll P, Goldman JE, Przedborski S, Schwartz RE, Ho DD, Studer L, Chen S. Han Y, et al. Res Sq [Preprint]. 2021 May 21:rs.3.rs-513461. doi: 10.21203/rs.3.rs-513461/v1. Res Sq. 2021. Update in: Cell Stem Cell. 2024 Feb 1;31(2):196-211.e6. doi: 10.1016/j.stem.2023.12.012 PMID: 34031650 Free PMC article. Updated. Preprint.
Phenotypic technologies in stem cell biology.
Vandana JJ, Lacko LA, Chen S. Vandana JJ, et al. Cell Chem Biol. 2021 Mar 18;28(3):257-270. doi: 10.1016/j.chembiol.2021.02.001. Epub 2021 Mar 1. Cell Chem Biol. 2021. PMID: 33651977 Free PMC article. Review.
SARS-CoV-2 infection induces beta cell transdifferentiation.
Tang X, Uhl S, Zhang T, Xue D, Li B, Vandana JJ, Acklin JA, Bonnycastle LL, Narisu N, Erdos MR, Bram Y, Chandar V, Chong ACN, Lacko LA, Min Z, Lim JK, Borczuk AC, Xiang J, Naji A, Collins FS, Evans T, Liu C, tenOever BR, Schwartz RE, Chen S. Tang X, et al. Cell Metab. 2021 Aug 3;33(8):1577-1591.e7. doi: 10.1016/j.cmet.2021.05.015. Epub 2021 May 19. Cell Metab. 2021. PMID: 34081913 Free PMC article.
Mechanisms of Lung Injury Induced by SARS-CoV-2 Infection.
Upadhya S, Rehman J, Malik AB, Chen S. Upadhya S, et al. Physiology (Bethesda). 2022 Mar 1;37(2):88-100. doi: 10.1152/physiol.00033.2021. Epub 2021 Oct 26. Physiology (Bethesda). 2022. PMID: 34698589 Free PMC article. Review.
17 results