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The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands.
Czimmerer Z, Halasz L, Daniel B, Varga Z, Bene K, Domokos A, Hoeksema M, Shen Z, Berger WK, Cseh T, Jambrovics K, Kolostyak Z, Fenyvesi F, Varadi J, Poliska S, Hajas G, Szatmari I, Glass CK, Bacsi A, Nagy L. Czimmerer Z, et al. Immunity. 2022 Nov 8;55(11):2006-2026.e6. doi: 10.1016/j.immuni.2022.10.004. Epub 2022 Nov 1. Immunity. 2022. PMID: 36323312 Free PMC article.
EGR2 is an epigenomic regulator of phagocytosis and antifungal immunity in alveolar macrophages.
Kolostyak Z, Bojcsuk D, Baksa V, Szigeti ZM, Bene K, Czimmerer Z, Boto P, Fadel L, Poliska S, Halasz L, Tzerpos P, Berger WK, Villabona-Rueda A, Varga Z, Kovacs T, Patsalos A, Pap A, Vamosi G, Bai P, Dezso B, Spite M, D'Alessio FR, Szatmari I, Nagy L. Kolostyak Z, et al. JCI Insight. 2024 Sep 10;9(17):e164009. doi: 10.1172/jci.insight.164009. JCI Insight. 2024. PMID: 39042472 Free PMC article.
Motif grammar: The basis of the language of gene expression.
Nagy G, Nagy L. Nagy G, et al. Comput Struct Biotechnol J. 2020 Jul 18;18:2026-2032. doi: 10.1016/j.csbj.2020.07.007. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32802274 Free PMC article. Review.
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