R01 DK052526/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 DK052526/DK/NIDDK NIH HHS/United States[Grant - PubMed

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ADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly.

Scott CM, Kruse KB, Schmidt BZ, Perlmutter DH, McCracken AA, Brodsky JL. Scott CM, et al. Mol Biol Cell. 2007 Oct;18(10):3776-87. doi: 10.1091/mbc.e07-01-0034. Epub 2007 Jul 18. Mol Biol Cell. 2007. PMID: 17634286 Free PMC article.

Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.

Burrows JA, Willis LK, Perlmutter DH. Burrows JA, et al. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1796-801. doi: 10.1073/pnas.97.4.1796. Proc Natl Acad Sci U S A. 2000. PMID: 10677536 Free PMC article.

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