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Page 1
Directed Biosynthesis of Mitragynine Stereoisomers.
Schotte C, Jiang Y, Grzech D, Dang TT, Laforest LC, León F, Mottinelli M, Nadakuduti SS, McCurdy CR, O'Connor SE. Schotte C, et al. J Am Chem Soc. 2023 Mar 8;145(9):4957-4963. doi: 10.1021/jacs.2c13644. Epub 2023 Feb 22. J Am Chem Soc. 2023. PMID: 36883326 Free PMC article.
Kratom Alkaloids: A Blueprint?
Smith KE, Sharma A, Grundmann O, McCurdy CR. Smith KE, et al. ACS Chem Neurosci. 2023 Jan 18;14(2):195-197. doi: 10.1021/acschemneuro.2c00704. Epub 2023 Jan 3. ACS Chem Neurosci. 2023. PMID: 36594896 Free PMC article.
Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands.
Shahbazi Nia S, Hossain MA, Ji G, Jonnalagadda SK, Obeng S, Rahman MA, Sifat AE, Nozohouri S, Blackwell C, Patel D, Thompson J, Runyon S, Hiranita T, McCurdy CR, McMahon L, Abbruscato TJ, Trippier PC, Neugebauer V, German NA. Shahbazi Nia S, et al. Eur J Med Chem. 2023 Jun 5;254:115309. doi: 10.1016/j.ejmech.2023.115309. Epub 2023 Mar 29. Eur J Med Chem. 2023. PMID: 37054561 Free PMC article.
Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids.
Obeng S, Kamble SH, Reeves ME, Restrepo LF, Patel A, Behnke M, Chear NJ, Ramanathan S, Sharma A, León F, Hiranita T, Avery BA, McMahon LR, McCurdy CR. Obeng S, et al. J Med Chem. 2020 Jan 9;63(1):433-439. doi: 10.1021/acs.jmedchem.9b01465. Epub 2019 Dec 27. J Med Chem. 2020. PMID: 31834797 Free PMC article.
Bioanalytical method development and validation of MES207, a neuropeptide FF receptor antagonist, and its application in preclinical pharmacokinetics.
King TI, Roewekamp AC, Sharma A, Harrison S, Mesangeau C, Mottinelli M, Kamble SH, McCurdy CR, Avery BA. King TI, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Dec 15;1134-1135:121875. doi: 10.1016/j.jchromb.2019.121875. Epub 2019 Nov 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 31790916 Free PMC article.
39 results