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BRCA1 participates in DNA decatenation.
Lou Z, Minter-Dykhouse K, Chen J. Lou Z, et al. Nat Struct Mol Biol. 2005 Jul;12(7):589-93. doi: 10.1038/nsmb953. Epub 2005 Jun 19. Nat Struct Mol Biol. 2005. PMID: 15965487
H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.
Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW. Franco S, et al. Mol Cell. 2006 Jan 20;21(2):201-14. doi: 10.1016/j.molcel.2006.01.005. Mol Cell. 2006. PMID: 16427010 Free article.