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NPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NFκB and JNK.
Leuk Lymphoma. 2015;56(12):3401-3406. doi: 10.3109/10428194.2015.1023799. Epub 2015 Oct 5.
Leuk Lymphoma. 2015.
PMID: 25791120
Free PMC article.
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
Rush EA, Pollock SL, Abecassis I, Redner RL.
Rush EA, et al.
Leuk Res. 2013 Dec;37(12):1704-10. doi: 10.1016/j.leukres.2013.09.024. Epub 2013 Sep 29.
Leuk Res. 2013.
PMID: 24183235
Free PMC article.
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Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.
Chattopadhyay A, Hood BL, Conrads TP, Redner RL.
Chattopadhyay A, et al.
Mol Cancer Res. 2014 Sep;12(9):1283-91. doi: 10.1158/1541-7786.MCR-14-0080. Epub 2014 Jul 17.
Mol Cancer Res. 2014.
PMID: 25033841
Free PMC article.
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