R01 CA257520/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	2
2022	1
2023	6
2024	5

1

CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.

Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, Zhou Y, Gao Q, Zhang L, Yan M, Sun Z, Fang D. Wang S, et al. J Clin Invest. 2023 Dec 1;133(23):e167728. doi: 10.1172/JCI167728. J Clin Invest. 2023. PMID: 38038129 Free PMC article.

2

Epinephrine promotes breast cancer metastasis through a ubiquitin-specific peptidase 22-mediated lipolysis circuit.

Zhou Y, Chu P, Wang Y, Li N, Gao Q, Wang S, Wei J, Xue G, Zhao Y, Jia H, Song J, Zhang Y, Pang Y, Zhu H, Sun J, Ma S, Su C, Hu B, Zhao Z, Zhang H, Lu J, Wang J, Wang H, Sun Z, Fang D. Zhou Y, et al. Sci Adv. 2024 Aug 16;10(33):eado1533. doi: 10.1126/sciadv.ado1533. Epub 2024 Aug 16. Sci Adv. 2024. PMID: 39151008 Free PMC article.

3

HRD1-mediated METTL14 degradation regulates m⁶A mRNA modification to suppress ER proteotoxic liver disease.

Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D. Wei J, et al. Mol Cell. 2021 Dec 16;81(24):5052-5065.e6. doi: 10.1016/j.molcel.2021.10.028. Epub 2021 Nov 29. Mol Cell. 2021. PMID: 34847358 Free PMC article.

4

CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4.

Chen S, Fan J, Xie P, Ahn J, Fernandez M, Billingham LK, Miska J, Wu JD, Wainwright DA, Fang D, Sosman JA, Wan Y, Zhang Y, Chandel NS, Zhang B. Chen S, et al. J Clin Invest. 2024 Mar 5;134(8):e170071. doi: 10.1172/JCI170071. J Clin Invest. 2024. PMID: 38441967 Free PMC article.

5

Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin.

Thepsuwan P, Bhattacharya A, Song Z, Hippleheuser S, Feng S, Wei X, Das NK, Sierra M, Wei J, Fang D, Huang YM, Zhang K, Shah YM, Sun S. Thepsuwan P, et al. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2212644120. doi: 10.1073/pnas.2212644120. Epub 2023 Jan 3. Proc Natl Acad Sci U S A. 2023. PMID: 36595688 Free PMC article.

6

Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.

Gao Q, Li N, Pan Y, Chu P, Zhou Y, Jia H, Cheng Y, Xue G, Song J, Zhang Y, Zhu H, Sun J, Zhang B, Sun Z, Fang D. Gao Q, et al. Cancer Lett. 2024 Nov 1;604:217196. doi: 10.1016/j.canlet.2024.217196. Epub 2024 Aug 31. Cancer Lett. 2024. PMID: 39222676 Free article.

7

ATXN3 deubiquitinates YAP1 to promote tumor growth.

Wang S, Liu K, Han X, Cheng Y, Zhao E, Brat DJ, Sun Z, Fang D. Wang S, et al. Am J Cancer Res. 2023 Sep 15;13(9):4222-4234. eCollection 2023. Am J Cancer Res. 2023. PMID: 37818078 Free PMC article.

8

Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients.

Hoffmann AD, Weinberg SE, Swaminathan S, Chaudhuri S, Almubarak HF, Schipma MJ, Mao C, Wang X, El-Shennawy L, Dashzeveg NK, Wei J, Mehl PJ, Shihadah LJ, Wai CM, Ostiguin C, Jia Y, D'Amico P, Wang NR, Luo Y, Demonbreun AR, Ison MG, Liu H, Fang D. Hoffmann AD, et al. Clin Immunol. 2023 Jul;252:109634. doi: 10.1016/j.clim.2023.109634. Epub 2023 May 5. Clin Immunol. 2023. PMID: 37150240 Free PMC article.

9

Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis.

Liu K, Gao Q, Jia Y, Wei J, Chaudhuri SM, Wang S, Tang A, Mani NL, Iyer R, Cheng Y, Gao B, Lu W, Sun Z, Zhang B, Liu H, Fang D. Liu K, et al. iScience. 2024 Jul 27;27(9):110592. doi: 10.1016/j.isci.2024.110592. eCollection 2024 Sep 20. iScience. 2024. PMID: 39246448 Free PMC article.

10

Acidity induces durable enhancement of T_reg cell suppressive functions for tumor immune evasion.

Mani NL, Weinberg SE, Chaudhuri S, Montauti E, Tang A, Iyer R, Fang D. Mani NL, et al. Mol Immunol. 2024 Oct;174:57-68. doi: 10.1016/j.molimm.2024.08.004. Epub 2024 Aug 29. Mol Immunol. 2024. PMID: 39213947

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