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Therapy-induced APOBEC3A drives evolution of persistent cancer cells.
Isozaki H, Sakhtemani R, Abbasi A, Nikpour N, Stanzione M, Oh S, Langenbucher A, Monroe S, Su W, Cabanos HF, Siddiqui FM, Phan N, Jalili P, Timonina D, Bilton S, Gomez-Caraballo M, Archibald HL, Nangia V, Dionne K, Riley A, Lawlor M, Banwait MK, Cobb RG, Zou L, Dyson NJ, Ott CJ, Benes C, Getz G, Chan CS, Shaw AT, Gainor JF, Lin JJ, Sequist LV, Piotrowska Z, Yeap BY, Engelman JA, Lee JJ, Maruvka YE, Buisson R, Lawrence MS, Hata AN. Isozaki H, et al. Nature. 2023 Aug;620(7973):393-401. doi: 10.1038/s41586-023-06303-1. Epub 2023 Jul 5. Nature. 2023. PMID: 37407818 Free PMC article.
Targeting therapy-persistent residual disease.
Sun X, Wu LF, Altschuler SJ, Hata AN. Sun X, et al. Nat Cancer. 2024 Sep;5(9):1298-1304. doi: 10.1038/s43018-024-00819-9. Epub 2024 Sep 17. Nat Cancer. 2024. PMID: 39289594 Review.
An extended APOBEC3A mutation signature in cancer.
Langenbucher A, Bowen D, Sakhtemani R, Bournique E, Wise JF, Zou L, Bhagwat AS, Buisson R, Lawrence MS. Langenbucher A, et al. Nat Commun. 2021 Mar 11;12(1):1602. doi: 10.1038/s41467-021-21891-0. Nat Commun. 2021. PMID: 33707442 Free PMC article.