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Page 1
An impaired ubiquitin-proteasome system increases APOBEC3A abundance.
Coxon M, Dennis MA, Dananberg A, Collins CD, Wilson HE, Meekma J, Savenkova MI, Ng D, Osbron CA, Mertz TM, Goodman AG, Duttke SH, Maciejowski J, Roberts SA. Coxon M, et al. NAR Cancer. 2023 Dec 19;5(4):zcad058. doi: 10.1093/narcan/zcad058. eCollection 2023 Dec. NAR Cancer. 2023. PMID: 38155930 Free PMC article.
Genetic inhibitors of APOBEC3B-induced mutagenesis.
Mertz TM, Rice-Reynolds E, Nguyen L, Wood A, Cordero C, Bray N, Harcy V, Vyas RK, Mitchell D, Lobachev K, Roberts SA. Mertz TM, et al. Genome Res. 2023 Sep;33(9):1568-1581. doi: 10.1101/gr.277430.122. Epub 2023 Aug 2. Genome Res. 2023. PMID: 37532520 Free PMC article.
Investigation of Break-Induced Replication in Yeast.
Osia B, Elango R, Kramara J, Roberts SA, Malkova A. Osia B, et al. Methods Mol Biol. 2021;2153:307-328. doi: 10.1007/978-1-0716-0644-5_22. Methods Mol Biol. 2021. PMID: 32840789 Free PMC article.
APOBEC-Induced Mutagenesis in Cancer.
Mertz TM, Collins CD, Dennis M, Coxon M, Roberts SA. Mertz TM, et al. Annu Rev Genet. 2022 Nov 30;56:229-252. doi: 10.1146/annurev-genet-072920-035840. Epub 2022 Aug 26. Annu Rev Genet. 2022. PMID: 36028227 Review.
Genomic footprints of activated telomere maintenance mechanisms in cancer.
Sieverling L, Hong C, Koser SD, Ginsbach P, Kleinheinz K, Hutter B, Braun DM, Cortés-Ciriano I, Xi R, Kabbe R, Park PJ, Eils R, Schlesner M; PCAWG-Structural Variation Working Group; Brors B, Rippe K, Jones DTW, Feuerbach L; PCAWG Consortium. Sieverling L, et al. Nat Commun. 2020 Feb 5;11(1):733. doi: 10.1038/s41467-019-13824-9. Nat Commun. 2020. PMID: 32024817 Free PMC article.
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Zhang Y, Chen F, Fonseca NA, He Y, Fujita M, Nakagawa H, Zhang Z, Brazma A; PCAWG Transcriptome Working Group; PCAWG Structural Variation Working Group; Creighton CJ; PCAWG Consortium. Zhang Y, et al. Nat Commun. 2020 Feb 5;11(1):736. doi: 10.1038/s41467-019-13885-w. Nat Commun. 2020. PMID: 32024823 Free PMC article.
21 results