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Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
Targeting telomerase for cancer therapy.
Guterres AN, Villanueva J. Guterres AN, et al. Oncogene. 2020 Sep;39(36):5811-5824. doi: 10.1038/s41388-020-01405-w. Epub 2020 Jul 30. Oncogene. 2020. PMID: 32733068 Free PMC article. Review.
Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma.
Reyes-Uribe P, Adrianzen-Ruesta MP, Deng Z, Echevarria-Vargas I, Mender I, Saheb S, Liu Q, Altieri DC, Murphy ME, Shay JW, Lieberman PM, Villanueva J. Reyes-Uribe P, et al. Oncogene. 2018 Jul;37(30):4058-4072. doi: 10.1038/s41388-018-0247-7. Epub 2018 Apr 26. Oncogene. 2018. PMID: 29695835 Free PMC article.
Tailoring Chemotherapy for the African-Centric S47 Variant of TP53.
Barnoud T, Budina-Kolomets A, Basu S, Leu JI, Good M, Kung CP, Liu J, Liu Q, Villanueva J, Zhang R, George DL, Murphy ME. Barnoud T, et al. Cancer Res. 2018 Oct 1;78(19):5694-5705. doi: 10.1158/0008-5472.CAN-18-1327. Epub 2018 Aug 16. Cancer Res. 2018. PMID: 30115697 Free PMC article.
Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma.
Echevarría-Vargas IM, Reyes-Uribe PI, Guterres AN, Yin X, Kossenkov AV, Liu Q, Zhang G, Krepler C, Cheng C, Wei Z, Somasundaram R, Karakousis G, Xu W, Morrissette JJ, Lu Y, Mills GB, Sullivan RJ, Benchun M, Frederick DT, Boland G, Flaherty KT, Weeraratna AT, Herlyn M, Amaravadi R, Schuchter LM, Burd CE, Aplin AE, Xu X, Villanueva J. Echevarría-Vargas IM, et al. EMBO Mol Med. 2018 May;10(5):e8446. doi: 10.15252/emmm.201708446. EMBO Mol Med. 2018. PMID: 29650805 Free PMC article.
COMBATING NRAS MUTANT MELANOMA: FROM BENCH TO BEDSIDE.
Echevarría-Vargas IM, Villanueva J. Echevarría-Vargas IM, et al. Melanoma Manag. 2017 Dec;4(4):183-186. doi: 10.2217/mmt-2017-0023. Epub 2017 Nov 21. Melanoma Manag. 2017. PMID: 29785260 Free PMC article. No abstract available.