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Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity.
Chen HM, van der Touw W, Wang YS, Kang K, Mai S, Zhang J, Alsina-Beauchamp D, Duty JA, Mungamuri SK, Zhang B, Moran T, Flavell R, Aaronson S, Hu HM, Arase H, Ramanathan S, Flores R, Pan PY, Chen SH. Chen HM, et al. J Clin Invest. 2018 Dec 3;128(12):5647-5662. doi: 10.1172/JCI97570. Epub 2018 Oct 22. J Clin Invest. 2018. PMID: 30352428 Free PMC article.
Potentiating Antitumor Efficacy Through Radiation and Sustained Intratumoral Delivery of Anti-CD40 and Anti-PDL1.
Liu HC, Viswanath DI, Pesaresi F, Xu Y, Zhang L, Di Trani N, Paez-Mayorga J, Hernandez N, Wang Y, Erm DR, Ho J, Susnjar A, Liu X, Demaria S, Chen SH, Teh BS, Butler EB, Xuan Chua CY, Grattoni A. Liu HC, et al. Int J Radiat Oncol Biol Phys. 2021 Jun 1;110(2):492-506. doi: 10.1016/j.ijrobp.2020.07.2326. Epub 2020 Aug 5. Int J Radiat Oncol Biol Phys. 2021. PMID: 32768562 Free PMC article.
Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling.
Butner JD, Martin GV, Wang Z, Corradetti B, Ferrari M, Esnaola N, Chung C, Hong DS, Welsh JW, Hasegawa N, Mittendorf EA, Curley SA, Chen SH, Pan PY, Libutti SK, Ganesan S, Sidman RL, Pasqualini R, Arap W, Koay EJ, Cristini V. Butner JD, et al. Elife. 2021 Nov 9;10:e70130. doi: 10.7554/eLife.70130. Elife. 2021. PMID: 34749885 Free PMC article.