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SETD2 safeguards the genome against isochromosome formation.
Mason FM, Kounlavong ES, Tebeje AT, Dahiya R, Guess T, Khan A, Vlach L, Norris SR, Lovejoy CA, Dere R, Strahl BD, Ohi R, Ly P, Walker CL, Rathmell WK. Mason FM, et al. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2303752120. doi: 10.1073/pnas.2303752120. Epub 2023 Sep 18. Proc Natl Acad Sci U S A. 2023. PMID: 37722039 Free PMC article.
Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids.
Vilgelm AE, Bergdorf K, Wolf M, Bharti V, Shattuck-Brandt R, Blevins A, Jones C, Phifer C, Lee M, Lowe C, Hongo R, Boyd K, Netterville J, Rohde S, Idrees K, Bauer JA, Westover D, Reinfeld B, Baregamian N, Richmond A, Rathmell WK, Lee E, McDonald OG, Weiss VL. Vilgelm AE, et al. iScience. 2020 Aug 21;23(8):101408. doi: 10.1016/j.isci.2020.101408. Epub 2020 Jul 24. iScience. 2020. PMID: 32771978 Free PMC article.
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.
Msaouel P, Malouf GG, Su X, Yao H, Tripathi DN, Soeung M, Gao J, Rao P, Coarfa C, Creighton CJ, Bertocchio JP, Kunnimalaiyaan S, Multani AS, Blando J, He R, Shapiro DD, Perelli L, Srinivasan S, Carbone F, Pilié PG, Karki M, Seervai RNH, Vokshi BH, Lopez-Terrada D, Cheng EH, Tang X, Lu W, Wistuba II, Thompson TC, Davidson I, Giuliani V, Schlacher K, Carugo A, Heffernan TP, Sharma P, Karam JA, Wood CG, Walker CL, Genovese G, Tannir NM. Msaouel P, et al. Cancer Cell. 2020 May 11;37(5):720-734.e13. doi: 10.1016/j.ccell.2020.04.002. Epub 2020 Apr 30. Cancer Cell. 2020. PMID: 32359397 Free PMC article.
A cytoskeletal function for PBRM1 reading methylated microtubules.
Karki M, Jangid RK, Anish R, Seervai RNH, Bertocchio JP, Hotta T, Msaouel P, Jung SY, Grimm SL, Coarfa C, Weissman BE, Ohi R, Verhey KJ, Hodges HC, Burggren W, Dere R, Park IY, Prasad BVV, Rathmell WK, Walker CL, Tripathi DN. Karki M, et al. Sci Adv. 2021 Apr 2;7(14):eabf2866. doi: 10.1126/sciadv.abf2866. Print 2021 Apr. Sci Adv. 2021. PMID: 33811077 Free PMC article.
An actin-WHAMM interaction linking SETD2 and autophagy.
Seervai RNH, Grimm SL, Jangid RK, Tripathi DN, Coarfa C, Walker CL. Seervai RNH, et al. Biochem Biophys Res Commun. 2021 Jun 18;558:202-208. doi: 10.1016/j.bbrc.2020.09.025. Epub 2020 Oct 6. Biochem Biophys Res Commun. 2021. PMID: 33036756 Free PMC article.
Dual Chromatin and Cytoskeletal Remodeling by SETD2.
Park IY, Powell RT, Tripathi DN, Dere R, Ho TH, Blasius TL, Chiang YC, Davis IJ, Fahey CC, Hacker KE, Verhey KJ, Bedford MT, Jonasch E, Rathmell WK, Walker CL. Park IY, et al. Cell. 2016 Aug 11;166(4):950-962. doi: 10.1016/j.cell.2016.07.005. Cell. 2016. PMID: 27518565 Free PMC article.
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
Seervai RNH, Jangid RK, Karki M, Tripathi DN, Jung SY, Kearns SE, Verhey KJ, Cianfrocco MA, Millis BA, Tyska MJ, Mason FM, Rathmell WK, Park IY, Dere R, Walker CL. Seervai RNH, et al. Sci Adv. 2020 Oct 2;6(40):eabb7854. doi: 10.1126/sciadv.abb7854. Print 2020 Oct. Sci Adv. 2020. PMID: 33008892 Free PMC article.
Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice.
Koenning M, Wang X, Karki M, Jangid RK, Kearns S, Tripathi DN, Cianfrocco M, Verhey KJ, Jung SY, Coarfa C, Ward CS, Kalish BT, Grimm SL, Rathmell WK, Mostany R, Dere R, Rasband MN, Walker CL, Park IY. Koenning M, et al. Brain. 2021 Sep 4;144(8):2527-2540. doi: 10.1093/brain/awab200. Brain. 2021. PMID: 34014281 Free PMC article.
17 results