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Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
Targeting mutant NRAS signaling pathways in melanoma.
Vu HL, Aplin AE. Vu HL, et al. Pharmacol Res. 2016 May;107:111-116. doi: 10.1016/j.phrs.2016.03.007. Epub 2016 Mar 15. Pharmacol Res. 2016. PMID: 26987942 Free PMC article. Review.
SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death.
Rosenbaum SR, Caksa S, Stefanski CD, Trachtenberg IV, Wilson HP, Wilski NA, Ott CA, Purwin TJ, Haj JI, Pomante D, Kotas D, Chervoneva I, Capparelli C, Aplin AE. Rosenbaum SR, et al. Mol Cancer Res. 2024 Feb 1;22(2):209-220. doi: 10.1158/1541-7786.MCR-23-0290. Mol Cancer Res. 2024. PMID: 37847239 Free PMC article.
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth.
Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE. Han A, et al. Cancers (Basel). 2023 Jun 30;15(13):3451. doi: 10.3390/cancers15133451. Cancers (Basel). 2023. PMID: 37444561 Free PMC article.
Roles of the BAP1 Tumor Suppressor in Cell Metabolism.
Han A, Purwin TJ, Aplin AE. Han A, et al. Cancer Res. 2021 Jun 1;81(11):2807-2814. doi: 10.1158/0008-5472.CAN-20-3430. Epub 2021 Jan 14. Cancer Res. 2021. PMID: 33446574 Free PMC article. Review.
FOXD3 Regulates VISTA Expression in Melanoma.
Rosenbaum SR, Knecht M, Mollaee M, Zhong Z, Erkes DA, McCue PA, Chervoneva I, Berger AC, Lo JA, Fisher DE, Gershenwald JE, Davies MA, Purwin TJ, Aplin AE. Rosenbaum SR, et al. Cell Rep. 2020 Jan 14;30(2):510-524.e6. doi: 10.1016/j.celrep.2019.12.036. Cell Rep. 2020. PMID: 31940493 Free PMC article.
29 results