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Page 1
Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
Targeting TEAD-ious resistance.
Ott CA, Aplin AE. Ott CA, et al. Trends Cancer. 2023 Oct;9(10):780-781. doi: 10.1016/j.trecan.2023.07.016. Epub 2023 Aug 3. Trends Cancer. 2023. PMID: 37543514 Free PMC article.
Packing a Punch against PD-L1.
Capparelli C, Aplin AE. Capparelli C, et al. Cancer Discov. 2022 Jun 2;12(6):1413-1415. doi: 10.1158/2159-8290.CD-22-0301. Cancer Discov. 2022. PMID: 35652219
MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping.
Filipescu D, Carcamo S, Agarwal A, Tung N, Humblin É, Goldberg MS, Vyas NS, Beaumont KG, Demircioglu D, Sridhar S, Ghiraldini FG, Capparelli C, Aplin AE, Salmon H, Sebra R, Kamphorst AO, Merad M, Hasson D, Bernstein E. Filipescu D, et al. Nat Cell Biol. 2023 Sep;25(9):1332-1345. doi: 10.1038/s41556-023-01208-7. Epub 2023 Aug 21. Nat Cell Biol. 2023. PMID: 37605008 Free PMC article.
The future of targeted kinase inhibitors in melanoma.
Caksa S, Baqai U, Aplin AE. Caksa S, et al. Pharmacol Ther. 2022 Nov;239:108200. doi: 10.1016/j.pharmthera.2022.108200. Epub 2022 May 2. Pharmacol Ther. 2022. PMID: 35513054 Free PMC article. Review.
Targeting mutant NRAS signaling pathways in melanoma.
Vu HL, Aplin AE. Vu HL, et al. Pharmacol Res. 2016 May;107:111-116. doi: 10.1016/j.phrs.2016.03.007. Epub 2016 Mar 15. Pharmacol Res. 2016. PMID: 26987942 Free PMC article. Review.
Site matters in metastatic melanoma.
Wilson HP, Aplin AE. Wilson HP, et al. Trends Cancer. 2023 Aug;9(8):603-605. doi: 10.1016/j.trecan.2023.05.007. Epub 2023 Jun 17. Trends Cancer. 2023. PMID: 37331825 Free PMC article.
SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death.
Rosenbaum SR, Caksa S, Stefanski CD, Trachtenberg IV, Wilson HP, Wilski NA, Ott CA, Purwin TJ, Haj JI, Pomante D, Kotas D, Chervoneva I, Capparelli C, Aplin AE. Rosenbaum SR, et al. Mol Cancer Res. 2024 Feb 1;22(2):209-220. doi: 10.1158/1541-7786.MCR-23-0290. Mol Cancer Res. 2024. PMID: 37847239 Free PMC article.
40 results